WB (Western Blot)
(TORC2 antibody (pAb) tested by Western blot. Detection of TORC2 by Western blot analysis. Whole cell extract (20 ug) of NIH/3T3 (lane 1) and HEK293 (lane 2) blotted with TORC2 antibody at a dilution of 1:2,000.)
Rabbit anti-Human, Mouse TORC2 Polyclonal Antibody | anti-TORC2 antibody
TORC2 antibody (pAb)
Gene Names
CRTC2; TORC2; TORC-2
Reactivity
Human, Mouse
Applications
Western Blot, Immunoprecipitation
Synonyms
TORC2, Antibody; TORC2 antibody (pAb); CRTC2; anti-TORC2 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Form/Format
Rabbit serum containing 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.
Applicable Applications for anti-TORC2 antibody
WB (Western Blot), IP (Immunoprecipitation)
Immunogen
This TORC2 antibody was raised against a peptide at the C-terminus of human TORC2.
Preparation and Storage
Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20 degree C for up to 2 years. Keep all reagents on ice when not in storage.1ug/ul
WB (Western Blot)
(TORC2 antibody (pAb) tested by Western blot. Detection of TORC2 by Western blot analysis. Whole cell extract (20 ug) of NIH/3T3 (lane 1) and HEK293 (lane 2) blotted with TORC2 antibody at a dilution of 1:2,000.)
WB (Western Blot)
(TORC2 antibody (pAb) tested by Western blot. Detection of TORC2 by Western blot analysis. Whole cell extract (20 ug) of NIH/3T3 (lane 1) and HEK293 (lane 2) blotted with TORC2 antibody at a dilution of 1:2,000.)
WB (Western Blot)
(TORC2 antibody (pAb) tested by Immunoprecipitation. 10 ul of TORC2 antibody was used to immunoprecipitate TORC2 from 400 ug of HEK293 whole cell extract (lane 2). 10 ul of rabbit IgG was used as a negative control (lane 1). The immunoprecipitated protein was detected by Western blotting using the TORC2 antibody at a dilution of 1:2,000.)
WB (Western Blot)
(TORC2 antibody (pAb) tested by Immunoprecipitation. 10 ul of TORC2 antibody was used to immunoprecipitate TORC2 from 400 ug of HEK293 whole cell extract (lane 2). 10 ul of rabbit IgG was used as a negative control (lane 1). The immunoprecipitated protein was detected by Western blotting using the TORC2 antibody at a dilution of 1:2,000.)
Related Product Information for anti-TORC2 antibody
Short Description: Our TORC2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunoprecipitation and Western blot; it has been shown to react with Human and Mouse samples.
Background: TORC2 (Transducer of regulated cAMP response element-binding protein 2)(CRTC2 or CREB-regulated transcription coactivator 2) is a coactivator of transcription through the CREB1 signaling pathway, independent of phosphorylation at serine 133. Involved in metabolic signaling pathways, it is responsive to glucagon signaling and regulates gluconeogenesis. It is a potent activator of mitochondrial biogenesis in muscle cells. TORC2 is inactivated by phosphorylation at serine 171 (in response to both insulin signaling and the activation of AMPK), which facilitates recognition by 14-3-3 protein and subsequent translocation to the cytoplasm.
Background: TORC2 (Transducer of regulated cAMP response element-binding protein 2)(CRTC2 or CREB-regulated transcription coactivator 2) is a coactivator of transcription through the CREB1 signaling pathway, independent of phosphorylation at serine 133. Involved in metabolic signaling pathways, it is responsive to glucagon signaling and regulates gluconeogenesis. It is a potent activator of mitochondrial biogenesis in muscle cells. TORC2 is inactivated by phosphorylation at serine 171 (in response to both insulin signaling and the activation of AMPK), which facilitates recognition by 14-3-3 protein and subsequent translocation to the cytoplasm.
Product Categories/Family for anti-TORC2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 67; 76 kDa
Observed: 70 kDa
Observed: 70 kDa
NCBI Official Full Name
CREB-regulated transcription coactivator 2
NCBI Official Synonym Full Names
CREB regulated transcription coactivator 2
NCBI Official Symbol
CRTC2
NCBI Official Synonym Symbols
TORC2; TORC-2
NCBI Protein Information
CREB-regulated transcription coactivator 2; transducer of regulated cAMP response element-binding protein (CREB) 2
UniProt Protein Name
CREB-regulated transcription coactivator 2
UniProt Gene Name
CRTC2
UniProt Synonym Gene Names
TORC2; TORC-2; Transducer of CREB protein 2
UniProt Entry Name
CRTC2_HUMAN
Similar Products
Product Notes
The TORC2 crtc2 (Catalog #AAA59928) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TORC2 antibody (pAb) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TORC2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IP (Immunoprecipitation). Researchers should empirically determine the suitability of the TORC2 crtc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TORC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.