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FCM/FACS (Flow Cytometry)
(TOX3 Antibody (Center) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Rabbit anti-Human, mouse TOX3 Polyclonal Antibody | anti-TOX3 antibody
TOX3 Antibody (Center)
Gene Names
TOX3; CAGF9; TNRC9
Reactivity
Human, mouse
Applications
Immunohistochemistry, Flow Cytometry, Functional Assay, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
TOX3, Antibody; TOX3 Antibody (Center); TOX high mobility group box family member 3; CAG trinucleotide repeat-containing gene F9 protein; Trinucleotide repeat-containing gene 9 protein; TOX3; CAGF9; TNRC9; anti-TOX3 antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This TOX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-242 amino acids from the Central region of human TOX3.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.48 (varies by lot)
Sequence Positions
214-242
Sequence Length
571
Applicable Applications for anti-TOX3 antibody
IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
FCM/FACS (Flow Cytometry)
(TOX3 Antibody (Center) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
FCM/FACS (Flow Cytometry)
(TOX3 Antibody (Center) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
WB (Western Blot)
(Western blot analysis of TOX3 Antibody (Center) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in mouse lung tissue lysate. TOX3 Antibody (Center) (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of TOX3 Antibody (Center) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in mouse lung tissue lysate. TOX3 Antibody (Center) (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of TOX3 Antibody (Center) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in MDA-MB453 cell line lysate. TOX3 Antibody (Center) (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of TOX3 Antibody (Center) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in MDA-MB453 cell line lysate. TOX3 Antibody (Center) (arrow) was detected using the purified Pab.)
IHC (Immunohiostchemistry)
(TOX3 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TOX3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(TOX3 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TOX3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(Western blot analysis of TOX3 Antibody (Center) in mouse stomach tissue lysates (35ug/lane). TOX3 (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of TOX3 Antibody (Center) in mouse stomach tissue lysates (35ug/lane). TOX3 (arrow) was detected using the purified Pab.)
Related Product Information for anti-TOX3 antibody
TOX3 contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer.
References
Wacholder, S., et al. N. Engl. J. Med. 362(11):986-993(2010)
Odefrey, F., et al. Cancer Res. 70(4):1449-1458(2010)
Couch, F.J., et al. Cancer Epidemiol. Biomarkers Prev. 18(11):3044-3048(2009)
Stacey, S.N., et al. Nat. Genet. 39(7):865-869(2007)
Odefrey, F., et al. Cancer Res. 70(4):1449-1458(2010)
Couch, F.J., et al. Cancer Epidemiol. Biomarkers Prev. 18(11):3044-3048(2009)
Stacey, S.N., et al. Nat. Genet. 39(7):865-869(2007)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
63342
NCBI Official Full Name
TOX high mobility group box family member 3 isoform 1
NCBI Official Synonym Full Names
TOX high mobility group box family member 3
NCBI Official Symbol
TOX3
NCBI Official Synonym Symbols
CAGF9; TNRC9
NCBI Protein Information
TOX high mobility group box family member 3
UniProt Protein Name
TOX high mobility group box family member 3
UniProt Gene Name
TOX3
UniProt Synonym Gene Names
CAGF9; TNRC9
UniProt Entry Name
TOX3_HUMAN
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Product Notes
The TOX3 tox3 (Catalog #AAA284991) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 214-242. The TOX3 Antibody (Center) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TOX3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the TOX3 tox3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TOX3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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