WB (Western Blot)
(Western blot analysis of extracts from COS7 cells (Lane 2) and HuvEc cells (Lane 3), using TRADD antiobdy. The lane on the left is treated with systhesized peptide.)
Rabbit anti-Human TRADD Polyclonal Antibody | anti-TRADD antibody
TRADD Antibody
Gene Names
TRADD; Hs.89862
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
TRADD, Antibody; TRADD Antibody; TNFRSF1A-associated via death domain; Tumor necrosis factor receptor type 1-associated DEATH domain protein; TNFR1-associated DEATH domain protein; anti-TRADD antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total TRADD protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
312
Applicable Applications for anti-TRADD antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from Internal of human TRADD.
Target Name
TRADD
Preparation and Storage
Store at -20 degree C
WB (Western Blot)
(Western blot analysis of extracts from COS7 cells (Lane 2) and HuvEc cells (Lane 3), using TRADD antiobdy. The lane on the left is treated with systhesized peptide.)
WB (Western Blot)
(Western blot analysis of extracts from COS7 cells (Lane 2) and HuvEc cells (Lane 3), using TRADD antiobdy. The lane on the left is treated with systhesized peptide.)
WB (Western Blot)
(Western blot analysis of extracts from COS7 cells, using TRADD antibody.)
WB (Western Blot)
(Western blot analysis of extracts from COS7 cells, using TRADD antibody.)
IHC (Immunohistochemistry)
(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using TRADD antibody.)
IHC (Immunohistochemistry)
(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using TRADD antibody.)
Related Product Information for anti-TRADD antibody
The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARFof CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARFof CDKN2A By similarity. Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.Hiroyasu Inada, J. Cell Biol., Oct 2001; 155: 415. Kenneth M. Izumi, Mol. Cell. Biol., Aug 1999; 19: 5759 - 5767. Susumu Rokudai, Mol. Cell. Biol., Dec 2002; 22: 8695 - 8708.
Product Categories/Family for anti-TRADD antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27,904 Da
NCBI Official Full Name
tumor necrosis factor receptor type 1-associated DEATH domain protein
NCBI Official Synonym Full Names
TNFRSF1A-associated via death domain
NCBI Official Symbol
TRADD
NCBI Official Synonym Symbols
Hs.89862
NCBI Protein Information
tumor necrosis factor receptor type 1-associated DEATH domain protein
UniProt Protein Name
Tumor necrosis factor receptor type 1-associated DEATH domain protein
UniProt Gene Name
TRADD
UniProt Synonym Gene Names
TNFR1-associated DEATH domain protein
UniProt Entry Name
TRADD_HUMAN
Similar Products
Product Notes
The TRADD tradd (Catalog #AAA305996) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRADD Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRADD can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the TRADD tradd for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRADD, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.