IHC (Immunohiostchemistry)
(TRAP1 Antibody (C-term) (AAA283792)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRAP1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human TRAP1 Polyclonal Antibody | anti-TRAP1 antibody
TRAP1 Antibody (C-term)
Gene Names
TRAP1; HSP75; HSP 75; HSP90L; TRAP-1
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
TRAP1, Antibody; TRAP1 Antibody (C-term); Heat shock protein 75 kDa; mitochondrial; HSP 75; TNFR-associated protein 1; Tumor necrosis factor type 1 receptor-associated protein; TRAP-1; TRAP1; HSP75; anti-TRAP1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This TRAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 542-570 amino acids from the C-terminal region of human TRAP1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
542-570
Sequence Length
651
Applicable Applications for anti-TRAP1 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(TRAP1 Antibody (C-term) (AAA283792)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRAP1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(TRAP1 Antibody (C-term) (AAA283792)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRAP1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(TRAP1 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the TRAP1 antibody detected the TRAP1 protein (arrow).)
WB (Western Blot)
(TRAP1 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the TRAP1 antibody detected the TRAP1 protein (arrow).)
Related Product Information for anti-TRAP1 antibody
HSP90 proteins are highly conserved molecular chaperones
that have key roles in signal transduction, protein folding,
protein degradation, and morphologic evolution. HSP90 proteins
normally associate with other cochaperones and play important roles
in folding newly synthesized proteins or stabilizing and refolding
denatured proteins after stress. TRAP1 is a mitochondrial HSP90
protein. Other HSP90 proteins are found in cytosol (see HSP90AA1;
MIM 140571) and endoplasmic reticulum (HSP90B1; MIM 191175) (Chen
et al., 2005 [PubMed 16269234]).
that have key roles in signal transduction, protein folding,
protein degradation, and morphologic evolution. HSP90 proteins
normally associate with other cochaperones and play important roles
in folding newly synthesized proteins or stabilizing and refolding
denatured proteins after stress. TRAP1 is a mitochondrial HSP90
protein. Other HSP90 proteins are found in cytosol (see HSP90AA1;
MIM 140571) and endoplasmic reticulum (HSP90B1; MIM 191175) (Chen
et al., 2005 [PubMed 16269234]).
Product Categories/Family for anti-TRAP1 antibody
References
Liu, D., et al. Cancer Lett. 296(2):194-205(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Nguyen, M.C., et al. Cancer Immunol. Immunother. 59(9):1313-1323(2010)
Landriscina, M., et al. Cancer Res. 70(16):6577-6586(2010)
Leav, I., et al. Am. J. Pathol. 176(1):393-401(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Nguyen, M.C., et al. Cancer Immunol. Immunother. 59(9):1313-1323(2010)
Landriscina, M., et al. Cancer Res. 70(16):6577-6586(2010)
Leav, I., et al. Am. J. Pathol. 176(1):393-401(2010)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
80110
NCBI Official Full Name
heat shock protein 75 kDa, mitochondrial isoform 1
NCBI Official Synonym Full Names
TNF receptor-associated protein 1
NCBI Official Symbol
TRAP1
NCBI Official Synonym Symbols
HSP75; HSP 75; HSP90L; TRAP-1
NCBI Protein Information
heat shock protein 75 kDa, mitochondrial
UniProt Protein Name
Heat shock protein 75 kDa, mitochondrial
UniProt Gene Name
TRAP1
UniProt Synonym Gene Names
HSP75; HSP 75; TRAP-1
UniProt Entry Name
TRAP1_HUMAN
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Product Notes
The TRAP1 trap1 (Catalog #AAA283792) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 542-570. The TRAP1 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRAP1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the TRAP1 trap1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRAP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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