WB (Western Blot)
(Anti-TREM1 antibody, AAA45188, Western blottingLane 1: Recombinant Mouse TREM1 Protein 1ng)
Rabbit anti-Mouse TREM1 Polyclonal Antibody | anti-TREM1 antibody
Anti-TREM1 antibody
Reactivity
Mouse
Applications
Immunohistochemistry, Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
TREM1, Antibody; Anti-TREM1 antibody; Triggering receptor expressed on myeloid cells 1(TREM-1); triggering receptor expressed on myeloid cells 1; CD354 antibody; OTTMUSP00000018206 antibody; TREM 1 antibody; TREM-1 antibody; TREM1 antibody; TREM1_HUMAN antibody; Triggering receptor expressed on monocytes 1 antibody; Triggering receptor expressed on myeloid cells 1 antibody; Triggering receptor TREM 1 antibody; Triggering receptor TREM1 antibody; anti-TREM1 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
230
Applicable Applications for anti-TREM1 antibody
IHC (Immunohistochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence in the middle of mouse TREM1 (74-90aa FTRPSEVHMGKFTLKHD).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
WB (Western Blot)
(Anti-TREM1 antibody, AAA45188, Western blottingLane 1: Recombinant Mouse TREM1 Protein 1ng)
WB (Western Blot)
(Anti-TREM1 antibody, AAA45188, Western blottingLane 1: Recombinant Mouse TREM1 Protein 1ng)
IHC (Immunohistochemistry)
(Anti-TREM1 antibody, AAA45188, IHC(P)IHC(P): Mouse Spleen Tissue)
IHC (Immunohistochemistry)
(Anti-TREM1 antibody, AAA45188, IHC(P)IHC(P): Mouse Spleen Tissue)
Related Product Information for anti-TREM1 antibody
Description: Rabbit IgG polyclonal antibody for Triggering receptor expressed on myeloid cells 1(TREM1) detection. Tested with WB, IHC-P, IHC-F in Mouse.
Background: Trem1, Triggering receptor expressed on myeloid cells-1, is encoded by Trem1 gene. The expression of Trem1 is in monocytes and neutrophils but not in lymphocytes, dendritic cells, or other cell types. Trem1 is a 30-kD glycoprotein that is reduced to 26 kD by deglycosylation, in agreement with the predicted molecular mass. The Trem1 gene which contains 4 exons maps to chromosome 6p21.1, within a TREM gene cluster and the mouse Trem1 gene maps to chromosome 17 in a region that shows homology of synteny to human chromosome 6. The expression of Trem1 is upregulated by stimulation with lipopolysaccharide(LPS), gram-negative bacteria, and fungi. Cross-linking of Trem1 on neutrophils induces interleukin-8(IL8) and myeloperoxidase secretion, while cross-linking on monocytes induces not only secretion of IL8 but also of monocyte chemotactic protein-1(MCP1, or SCYA2) and tumor necrosis factor(TNF); MCP1 and TNF secretion could be further upregulated by LPS-mediated priming. Trem1 engagement also induces upregulation of adhesion molecules(e.g., ITGB1) and costimulatory molecules(e.g., CD40). Trem1 is associated with DAP12(TYROBP), a molecule frequently associated with activating receptors.
Background: Trem1, Triggering receptor expressed on myeloid cells-1, is encoded by Trem1 gene. The expression of Trem1 is in monocytes and neutrophils but not in lymphocytes, dendritic cells, or other cell types. Trem1 is a 30-kD glycoprotein that is reduced to 26 kD by deglycosylation, in agreement with the predicted molecular mass. The Trem1 gene which contains 4 exons maps to chromosome 6p21.1, within a TREM gene cluster and the mouse Trem1 gene maps to chromosome 17 in a region that shows homology of synteny to human chromosome 6. The expression of Trem1 is upregulated by stimulation with lipopolysaccharide(LPS), gram-negative bacteria, and fungi. Cross-linking of Trem1 on neutrophils induces interleukin-8(IL8) and myeloperoxidase secretion, while cross-linking on monocytes induces not only secretion of IL8 but also of monocyte chemotactic protein-1(MCP1, or SCYA2) and tumor necrosis factor(TNF); MCP1 and TNF secretion could be further upregulated by LPS-mediated priming. Trem1 engagement also induces upregulation of adhesion molecules(e.g., ITGB1) and costimulatory molecules(e.g., CD40). Trem1 is associated with DAP12(TYROBP), a molecule frequently associated with activating receptors.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
25,409 Da
NCBI Official Full Name
Triggering receptor expressed on myeloid cells 1
NCBI Official Synonym Full Names
triggering receptor expressed on myeloid cells 1
NCBI Official Symbol
Trem1
NCBI Protein Information
triggering receptor expressed on myeloid cells 1; triggering receptor expressed in monocytes 1
UniProt Protein Name
Triggering receptor expressed on myeloid cells 1
UniProt Gene Name
Trem1
UniProt Synonym Gene Names
TREM-1
UniProt Entry Name
TREM1_MOUSE
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Product Notes
The TREM1 trem1 (Catalog #AAA45188) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-TREM1 antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TREM1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the TREM1 trem1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TREM1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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