IF (Immunofluorescence)
(Immunofluorescence of TRIP12 in rat colon tissue with TRIP12 antibody at 20 μg/ml.)
Rabbit TRIP12 Polyclonal Antibody | anti-TRIP12 antibody
TRIP12 Antibody
Gene Names
TRIP12; ULF; TRIP-12
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
TRIP12 antibody is affinity chromatography purified via peptide column.
Synonyms
TRIP12, Antibody; TRIP12 Antibody; TRIP12; ULF; TRIP-12; KIAA0045; E3 ubiquitin-protein ligase TRIP12; E3 ubiquitin-protein ligase for Arf; Thyroid hormone receptor interactor 12; anti-TRIP12 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
TRIP12 antibody is human, mouse and rat reactive. At least four isoforms are known to exist.
Purity/Purification
TRIP12 antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
1992
Applicable Applications for anti-TRIP12 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
TRIP12 antibody was raised against a 18 amino acid peptide near the carboxy terminus of human TRIP12.
Buffer
TRIP12 antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
Antibody can be stored at 4 degree C up to one year. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of TRIP12 in rat colon tissue with TRIP12 antibody at 20 μg/ml.)
IF (Immunofluorescence)
(Immunofluorescence of TRIP12 in rat colon tissue with TRIP12 antibody at 20 μg/ml.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of TRIP12 in rat colon tissue with TRIP12 antibody at 5 μg/ml.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of TRIP12 in rat colon tissue with TRIP12 antibody at 5 μg/ml.)
WB (Western Blot)
(Western blot analysis of TRIP12 in rat colon tissue lysate with TRIP12 antibody at 1 μg/ml.)
WB (Western Blot)
(Western blot analysis of TRIP12 in rat colon tissue lysate with TRIP12 antibody at 1 μg/ml.)
Related Product Information for anti-TRIP12 antibody
Thyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner (1). TRIP12 (thyroid hormone receptor interactor 12) is an ATP-dependent E3 ubiquitin ligase involved in the human ubiquitin fusion degradation (UFD) pathway and also modulates the NEDD8 pathway (2,3). TRIP12 contains one WWE domain and a single HECT (E6AP-type E3 ubiquitin-protein ligase) domain suggested to contain a noncovalent ubiquitin-binding site (4). TRIP12 acts as a key regulator of DNA damage response and the ubiquitin ligase activity of TRIP12 is essential for mouse development (5).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 219 kDa
Observed: 220 kDa
Observed: 220 kDa
NCBI Official Full Name
E3 ubiquitin-protein ligase TRIP12 isoform c
NCBI Official Synonym Full Names
thyroid hormone receptor interactor 12
NCBI Official Symbol
TRIP12
NCBI Official Synonym Symbols
ULF; TRIP-12
NCBI Protein Information
E3 ubiquitin-protein ligase TRIP12; TR-interacting protein 12; E3 ubiquitin-protein ligase for Arf; thyroid receptor interacting protein 12; thyroid receptor-interacting protein 12; probable E3 ubiquitin-protein ligase TRIP12
UniProt Protein Name
E3 ubiquitin-protein ligase TRIP12
UniProt Gene Name
TRIP12
UniProt Synonym Gene Names
KIAA0045; ULF; ULF; TR-interacting protein 12; TRIP-12
UniProt Entry Name
TRIPC_HUMAN
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Product Notes
The TRIP12 trip12 (Catalog #AAA40708) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TRIP12 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TRIP12 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the TRIP12 trip12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRIP12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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