IHC (Immunohistochemisry)
(Anti-TSH Receptor / TSHR antibody IHC of human Thyroid, Papillary Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit TSH Receptor / TSHR Polyclonal Antibody | anti-TSHR antibody
Rabbit Polyclonal to Human TSH Receptor / TSHR
Gene Names
TSHR; LGR3; CHNG1; hTSHR-I
Reactivity
HumanPredicted Reactivity: Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Bat, Dog, Guinea pig, Horse, Pig (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
TSH Receptor / TSHR, Antibody; Rabbit Polyclonal to Human TSH Receptor / TSHR; Anti-TSH Receptor / TSHR Antibody (C-Terminus) IHC-plus; TSHR; CHNG1; HTSHR-I; LGR3; Thyrotrophin receptor; TSH-R; TSH receptor; Thyrotropin receptor; Human TSH Receptor; anti-TSHR antibody
Host
Rabbit
Reactivity
Human
Predicted Reactivity: Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Bat, Dog, Guinea pig, Horse, Pig (at least 90% immunogen sequence identity)
Predicted Reactivity: Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Bat, Dog, Guinea pig, Horse, Pig (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human TSH Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except LHCGR (42%).
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
764
Applicable Applications for anti-TSHR antibody
IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
Synthetic 19 amino acid peptide from C-terminus of human TSH Receptor. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Bat, Dog, Elephant, Horse, Pig, Guinea pig (94%).
Immunogen Type
Synthetic peptide
Immunogen
TSH Receptor / TSHR antibody was raised against synthetic 19 amino acid peptide from C-terminus of human TSH Receptor. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Bat, Dog, Elephant, Horse, Pig, Guinea pig (94%); Mouse, Rat, Sheep, Cat, Bovine, Hamster, Panda, Rabbit, Opossum (89%).
Antigen Modification
C-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
IHC (Immunohistochemisry)
(Anti-TSH Receptor / TSHR antibody IHC of human Thyroid, Papillary Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohistochemisry)
(Anti-TSH Receptor / TSHR antibody IHC of human Thyroid, Papillary Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohiostchemistry)
(Anti-TSH Receptor / TSHR antibody IHC of human Thyroid, Follicular Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohiostchemistry)
(Anti-TSH Receptor / TSHR antibody IHC of human Thyroid, Follicular Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohistochemistry)
(Anti-TSH Receptor antibody IHC of human thyroid, follicular epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohistochemistry)
(Anti-TSH Receptor antibody IHC of human thyroid, follicular epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-TSHR antibody
Thyrotropin Receptor, a Glycoprotein Hormone Receptor, plays a central role in controlling thyroid cell metabolism. The TSH receptor can interact with both TSH and autoantibodies against the TSH receptor (thyroid-stimulating immunoglobulins, TSI). Mutations in the receptor are the cause for hyperthyroidism such as gestational hyperthyroidism (hypersensitivity to chorionic gonadotropin) and Grave's disease (autoimmune hyperthyroidism).
Product Categories/Family for anti-TSHR antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30,800 Da
NCBI Official Full Name
thyrotropin receptor isoform 1
NCBI Official Synonym Full Names
thyroid stimulating hormone receptor
NCBI Official Symbol
TSHR
NCBI Official Synonym Symbols
LGR3; CHNG1; hTSHR-I
NCBI Protein Information
thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; seven transmembrane helix receptor; thyroid stimulating hormone receptor, isoform 2
UniProt Protein Name
Thyrotropin receptor
UniProt Gene Name
TSHR
UniProt Synonym Gene Names
LGR3; TSH-R
UniProt Entry Name
TSHR_HUMAN
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Product Notes
The TSHR tshr (Catalog #AAA52068) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human TSH Receptor / TSHR reacts with Human Predicted Reactivity: Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Bat, Dog, Guinea pig, Horse, Pig (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's TSH Receptor / TSHR can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the TSHR tshr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TSH Receptor / TSHR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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