Rabbit anti-Mouse TSLP Receptor Polyclonal Antibody | anti-Crlf2 antibody

TSLP Receptor Antibody

Cat. Num. AAA40099

• Gene Names: Crlf2; CRLM2; Ly114; Tpte2; Tslpr
• Reactivity: Mouse
• Applications: Immunofluorescence, Western Blot, ELISA
• Purity: TSLP Receptor Antibody is affinity chromatography purified via peptide column.
• Synonyms: TSLP Receptor, Antibody; TSLP Receptor Antibody; TSLP Receptor; CRLM2; Ly114; Tpte2; Tslpr; Crlm2; Cytokine receptor-like factor 2; Cytokine receptor-like molecule 2; CRLM-2; cytokine receptor-like factor 2; anti-Crlf2 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: TSLP Receptor Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 359

• Applicable Applications for anti-Crlf2 antibody: IF (Immunofluorescence), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: TSLP receptor antibody was raised against a 21 amino acid synthetic peptide from near the center of mouse TSLP receptor.
• Buffer: TSLP Receptor Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: TSLP Receptor antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of TSLP Receptor in Mouse Liver cells with TSLP Receptor antibody at 20 μg/mL.)

WB (Western Blot)

(Western blot analysis of TSLP Receptor in mouse heart tissue lysate with TSLP Receptor antibody at 1 μg/mL in (A) the presence and (B) the absence of blocking peptide.)

Related Product Information for anti-Crlf2 antibody

TSLP Receptor Antibody: Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. It is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Its receptor TSLP-R will bind TSLP in a low-affinity fashion in transfected cells; co-transfection with IL-7R-alpha cDNA results in high-affinity binding and a functional heteromeric complex. This heteromeric receptor requires stat5 for TSLP-mediated signal transduction and is inhibited by SOCS-1. The approximately 75 kDa band seen in the immunoblot may be a post-translationally modified form of TSLP-R.

NCBI and Uniprot Product Information

• NCBI GI #: 31980663
• NCBI GeneID: 57914
• NCBI Accession #: NP_057924
• NCBI GenBank Nucleotide #: NM_016715.3
• UniProt Accession #: Q8CII9; Q9CRJ6; Q9JIE7; Q9JIQ7; Q9JJH8; Q9JMD5
• Molecular Weight: 13,236 Da
• NCBI Official Full Name: cytokine receptor-like factor 2
• NCBI Official Synonym Full Names: cytokine receptor-like factor 2
• NCBI Official Symbol: Crlf2
• NCBI Official Synonym Symbols: CRLM2; Ly114; Tpte2; Tslpr
• NCBI Protein Information: cytokine receptor-like factor 2; CRLM-2; delta 1; TSLP receptor; lymphocyte antigen 114; type I cytokine receptor delta 1; cytokine receptor-like molecule 2; thymic stromal lymphopoietin protein receptor; thymic stromal-derived lymphopoietin, receptor; transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
• UniProt Protein Name: Cytokine receptor-like factor 2
• UniProt Gene Name: Crlf2
• UniProt Synonym Gene Names: Crlm2; Tpte2; Tslpr; CRLM-2; TSLP receptor
• UniProt Entry Name: CRLF2_MOUSE