IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human brain tissue using TTBK1 Polyclonal Antibody at dilution 1:35)
Rabbit anti-Human TTBK1 Polyclonal Antibody | anti-TTBK1 antibody
TTBK1 Polyclonal Antibody
Gene Names
TTBK1; BDTK
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
TTBK1, Antibody; TTBK1 Polyclonal Antibody; BDTK; anti-TTBK1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Concentration
2.3mg/ml (varies by lot)
Sequence Length
1321
Applicable Applications for anti-TTBK1 antibody
IHC (Immunohistochemistry), ELISA
Immunogen
Synthetic peptide of human TTBK1
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-133330 / sc-133331
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human brain tissue using TTBK1 Polyclonal Antibody at dilution 1:35)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human brain tissue using TTBK1 Polyclonal Antibody at dilution 1:35)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TTBK1 Polyclonal Antibody at dilution 1:35)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TTBK1 Polyclonal Antibody at dilution 1:35)
Related Product Information for anti-TTBK1 antibody
TTBK1 (tau tubulin kinase 1), also known as BDTK (brain-derived tau kinase), is a 1, 321 amino acid protein that contains one protein kinase domain and belongs to the serine/threonine protein kinase family. Localized to the cytoplasm and expressed at high levels in brain and at lower levels in testis and spinal cord, TTBK1 functions as a serine/threonine kinase that can phosphorylate Tau (a protein involved in tubulin polymerization) on threonine, tyrosine and serine residues. Specifically, TTBK1 uses divalent cations, such as magnesium and manganese, to catalyze the ATP-dependent transfer of a phosphate group onto Tau, creating a phosphoprotein and ADP. Phosphorylation of Tau causes its aggregation and subsequent loss of function, suggesting an important role for TTBK1 in the control of tubulin dynamics.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
69,084 Da
NCBI Official Full Name
tau-tubulin kinase 1
NCBI Official Synonym Full Names
tau tubulin kinase 1
NCBI Official Symbol
TTBK1
NCBI Official Synonym Symbols
BDTK
NCBI Protein Information
tau-tubulin kinase 1
UniProt Protein Name
Tau-tubulin kinase 1
UniProt Gene Name
TTBK1
UniProt Synonym Gene Names
BDTK; KIAA1855
UniProt Entry Name
TTBK1_HUMAN
Similar Products
Product Notes
The TTBK1 ttbk1 (Catalog #AAA173280) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TTBK1 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TTBK1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the TTBK1 ttbk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TTBK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.