WB (Western Blot)
(Western blot analysis of extracts of HepG2 cells, using UQCRC1 antibody.)
Rabbit UQCRC1 Polyclonal Antibody | anti-UQCRC1 antibody
UQCRC1 Antibody
Gene Names
UQCRC1; QCR1; UQCR1; D3S3191
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
UQCRC1, Antibody; UQCRC1 Antibody; Complex III subunit 1; Core protein I; Cytochrome b-c1 complex subunit 1; cytochrome b-c1 complex subunit 1, mitochondrial; D3S3191; mitochondrial; OTTHUMP00000164820; QCR1; QCR1_HUMAN; Ubiquinol cytochrome c reductase complex core protein 1; ubiquinol-cytochrome c reductase core protein I; Ubiquinol-cytochrome-c reductase complex core protein 1; UQCR1; Uqcrc1; anti-UQCRC1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
UQCRC1 antibody detects endogenous levels of UQCRC1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
480
Applicable Applications for anti-UQCRC1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthesized peptide derived from human UQCRC1.
Subcellular Location
Mitochondrion Inner Membrane.
Predicted Cross Reactivity
Pig, Bovine, Horse, Sheep, Rabbit, Dog
Similarity
Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
WB (Western Blot)
(Western blot analysis of extracts of HepG2 cells, using UQCRC1 antibody.)
WB (Western Blot)
(Western blot analysis of extracts of HepG2 cells, using UQCRC1 antibody.)
IHC (Immunohiostchemistry)
(AAA323162 at 1/100 staining Human lymph cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)
IHC (Immunohiostchemistry)
(AAA323162 at 1/100 staining Human lymph cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)
WB (Western Blot)
(Western blot analysis of extracts from various samples, using UQCRC1 antibody. Lane 1: rat brain treated with blocking peptide. Lane 2: Rat brain; Lane 3: 293; Lane 4: Mouse myeloma; Lane 5: B16F10;)
WB (Western Blot)
(Western blot analysis of extracts from various samples, using UQCRC1 antibody. Lane 1: rat brain treated with blocking peptide. Lane 2: Rat brain; Lane 3: 293; Lane 4: Mouse myeloma; Lane 5: B16F10;)
Related Product Information for anti-UQCRC1 antibody
Function: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.
Subunit Structure: The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1).
Similarity: Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily.
Subunit Structure: The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1).
Similarity: Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 45 kDa
Predicted: 53 kDa
Predicted: 53 kDa
NCBI Official Full Name
cytochrome b-c1 complex subunit 1, mitochondrial
NCBI Official Synonym Full Names
ubiquinol-cytochrome c reductase core protein 1
NCBI Official Symbol
UQCRC1
NCBI Official Synonym Symbols
QCR1; UQCR1; D3S3191
NCBI Protein Information
cytochrome b-c1 complex subunit 1, mitochondrial
UniProt Protein Name
Cytochrome b-c1 complex subunit 1, mitochondrial
UniProt Gene Name
UQCRC1
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Product Notes
The UQCRC1 uqcrc1 (Catalog #AAA323162) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The UQCRC1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's UQCRC1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the UQCRC1 uqcrc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UQCRC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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