Rabbit anti-Human VWA2 Polyclonal Antibody | anti-VWA2 antibody

VWA2 Antibody (N-term)

Cat. Num. AAA288589

• Gene Names: VWA2; AMACO; NET42; CCSP-2
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Synonyms: VWA2, Antibody; VWA2 Antibody (N-term); von Willebrand factor A domain-containing protein 2; A domain-containing protein similar to matrilin and collagen; AMACO; Colon cancer secreted protein 2; CCSP-2; VWA2; anti-VWA2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: This VWA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-72 amino acids from the N-terminal region of human VWA2.
• Purity/Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Sequence Positions: 44-72
• Sequence Length: 755

• Applicable Applications for anti-VWA2 antibody: ELISA, WB (Western Blot)
• Cellular Location: Secreted.
• Tissue Location: Expression is generally absent in normal colon and other normal body tissues, but it is induced an average of 78-fold in Stage II, III, and IV colon cancers, as well as in colon adenomas and colon cancer cell lines
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

WB (Western Blot)

(VWA2 Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the VWA2 antibody detected the VWA2 protein (arrow).)

WB (Western Blot)

(All lanes : Anti-VWA2 Antibody (N-term) at 1:1000 dilutionLane 1: A549 whole cell lysateLane 2: HL-60 whole cell lysate Lysates/proteins at 20 ug per lane.Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 82 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Related Product Information for anti-VWA2 antibody

VWA2, also named as AMACO and CCSP2, is a novel candidate serological marker of colon neoplasia. VWA2 is found in the media of variesy of established cell lines of both fibroblast and epithelial origin.

Product Categories/Family for anti-VWA2 antibody

Cancer

References

Gao, W., et al. Blood 112(5):1713-1719(2008)
Gebauer, J.M., et al. J. Biol. Chem. 283(26):17846-17854(2008)
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Xin, B., et al. Oncogene 24(4):724-731(2005)
Eller, E., et al. Ann. N. Y. Acad. Sci. 1037, 145-149 (2004) :

NCBI and Uniprot Product Information

• NCBI GI #: 440546401
• NCBI GeneID: 340706
• NCBI Accession #: NP_001258975.1
• NCBI GenBank Nucleotide #: NM_001272046.1
• UniProt Accession #: Q5GFL6; Q6ZS39; Q6ZWJ7; Q708C5; Q70UZ8; A1A5D4; B5MDJ8
• Molecular Weight: 82012
• NCBI Official Full Name: von Willebrand factor A domain-containing protein 2
• NCBI Official Synonym Full Names: von Willebrand factor A domain containing 2
• NCBI Official Symbol: VWA2
• NCBI Official Synonym Symbols: AMACO; NET42; CCSP-2
• NCBI Protein Information: von Willebrand factor A domain-containing protein 2
• UniProt Protein Name: von Willebrand factor A domain-containing protein 2
• UniProt Gene Name: VWA2
• UniProt Synonym Gene Names: AMACO; AMACO; CCSP-2
• UniProt Entry Name: VWA2_HUMAN