IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using at dilution 1/60.)
Rabbit anti-Human VWA5A Polyclonal Antibody | anti-VWA5A antibody
VWA5A Antibody
Gene Names
VWA5A; BCSC1; BCSC-1; LOH11CR2A
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Antigen affinity purification.
Synonyms
VWA5A, Antibody; VWA5A Antibody; BCSC1; BCSC-1; LOH11CR2A; anti-VWA5A antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total VWA5A protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
2.2 mg/ml (varies by lot)
Sequence Length
786
Applicable Applications for anti-VWA5A antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Recombinant Protein
Immunogen Description
Fusion protein corresponding to residues near the C terminal of human von Willebrand factor A domain containing 5A
Target Name
VWA5A
Preparation and Storage
Store at -20 degree C
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using at dilution 1/60.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using at dilution 1/60.)
Application Data
(Gel: 6%SDS-PAGE Lysates (from left to right): Adrenal pheochromocytoma tissue,Jurkat and A549 cell)
Application Data
(Gel: 6%SDS-PAGE Lysates (from left to right): Adrenal pheochromocytoma tissue,Jurkat and A549 cell)
Related Product Information for anti-VWA5A antibody
VWA5A (von Willebrand factor A domain containing 5A), also known as BCSC-1 (breast cancer suppressor candidate 1) or LOH11CR2A (loss of heterozygosity 11 chromosomal region 2 gene A protein), is a 786 amino acid protein containing one VIT domain and one VWFA domain. VWA5A is expressed at low levels in various tissues, with no expression found in 80% of tumor cell lines. Likely acting as a tumor suppressor gene, deletion of VWA5A leads to loss of heterozygosity (LOH) in breast and ovarian tumors, and may have an important role as a potential gene therapy target. Abnormal expression of VWA5A may lead to an increase in adhesion of CNE-2L2 cells associated with an increase in expression of E-cadherin, alpha-catenin, and p53, resulting in a decrease of malignant activity in cells with ectopic expression of VWA5A.
Product Categories/Family for anti-VWA5A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
29,235 Da
NCBI Official Full Name
von Willebrand factor A domain-containing protein 5A isoform 1
NCBI Official Synonym Full Names
von Willebrand factor A domain containing 5A
NCBI Official Symbol
VWA5A
NCBI Official Synonym Symbols
BCSC1; BCSC-1; LOH11CR2A
NCBI Protein Information
von Willebrand factor A domain-containing protein 5A
UniProt Protein Name
von Willebrand factor A domain-containing protein 5A
UniProt Gene Name
VWA5A
UniProt Synonym Gene Names
BCSC1; LOH11CR2A; BCSC-1
UniProt Entry Name
VMA5A_HUMAN
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Product Notes
The VWA5A vwa5a (Catalog #AAA302506) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The VWA5A Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's VWA5A can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the VWA5A vwa5a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VWA5A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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