IF (Immunofluorescence)
(Immunofluorescence of WAC in mouse testis tissue with WAC antibody at 5 μg/ml.)
Rabbit WAC Polyclonal Antibody | anti-WAC antibody
WAC Antibody
Gene Names
WAC; Wwp4; BM-016; PRO1741
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
WAC Antibody is affinity chromatography purified via peptide column.
Synonyms
WAC, Antibody; WAC Antibody; WAC; Wwp4; BM-016; PRO1741; KIAA1844; WW domain-containing adapter protein with coiled-coil; WW domain containing adaptor with coiled-coil; anti-WAC antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
At least two isoforms of WAC are known to exist; this antibody will detect the larger isoform.
Purity/Purification
WAC Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
647
Applicable Applications for anti-WAC antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
WAC antibody was raised against a 19 amino acid peptide near the center of human WAC.
Buffer
WAC Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
WAC antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
IF (Immunofluorescence)
(Immunofluorescence of WAC in mouse testis tissue with WAC antibody at 5 μg/ml.)
IF (Immunofluorescence)
(Immunofluorescence of WAC in mouse testis tissue with WAC antibody at 5 μg/ml.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of WAC in mouse testis tissue with WAC antibody at 2.5 μg/ml.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of WAC in mouse testis tissue with WAC antibody at 2.5 μg/ml.)
WB (Western Blot)
(Western blot analysis of WAC in human testis tissue lysate with WAC antibody at 1 μg/mL.)
WB (Western Blot)
(Western blot analysis of WAC in human testis tissue lysate with WAC antibody at 1 μg/mL.)
Related Product Information for anti-WAC antibody
WAC Antibody: The WW domain containing adaptor with coiled-coil protein (WAC) contains a WW domain that mediates protein-protein interactions and colocalizes with RNA splicing factor SC35. Further studies have indicated that WAC is a functional partner of the RNF20/40 complex that ubiquitinates Histone H2B, and that WAC regulates H2B ubiquitination. WAC targets RNF20/40 to associate with RNA polymerase II complex for H2B ubiquitination at active transcription sites. WAC-dependent transcription is also important for cell-cycle checkpoint activation in response to genotoxic stress.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Predicted: 71 kDa
Observed: 75 kDa
Observed: 75 kDa
NCBI Official Full Name
WW domain-containing adapter protein with coiled-coil isoform 1
NCBI Official Synonym Full Names
WW domain containing adaptor with coiled-coil
NCBI Official Symbol
WAC
NCBI Official Synonym Symbols
Wwp4; BM-016; PRO1741
NCBI Protein Information
WW domain-containing adapter protein with coiled-coil
UniProt Protein Name
WW domain-containing adapter protein with coiled-coil
UniProt Gene Name
WAC
UniProt Synonym Gene Names
KIAA1844
UniProt Entry Name
WAC_HUMAN
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Product Notes
The WAC wac (Catalog #AAA40646) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The WAC Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's WAC can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the WAC wac for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "WAC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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