FCM/FACS (Flow Cytometry)
(WDR37 Antibody (C-term) (AAA285487) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Rabbit WDR37 Polyclonal Antibody | anti-WDR37 antibody
WDR37 Antibody (C-term)
Reactivity
Human (Predicted Reactivity: Mouse)
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
WDR37, Antibody; WDR37 Antibody (C-term); WD repeat-containing protein 37; WDR37; KIAA0982; anti-WDR37 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse)
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
This WDR37 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 426-455 amino acids from the C-terminal region of human WDR37.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Positions
426-455
Sequence Length
264
Applicable Applications for anti-WDR37 antibody
FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Function
Required for normal ER Ca2+ handling in lymphocytes. Together with PACS1, it plays an essential role in stabilizing peripheral lymphocyte populations.
Cellular Location
Cytoplasm, nucleus.
Note: Primarily localized in the cytoplasm with the highest concentration in the perinuclear region and in small clusters at the leading edge of the spreading cells.
Note: Primarily localized in the cytoplasm with the highest concentration in the perinuclear region and in small clusters at the leading edge of the spreading cells.
Preparation and Storage
Maintain refrigerated at 2-8 degrees C for up to 2 weeks. For long term storage, store at -20 degrees C in small aliquots to prevent freeze-thaw cycles.
FCM/FACS (Flow Cytometry)
(WDR37 Antibody (C-term) (AAA285487) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
FCM/FACS (Flow Cytometry)
(WDR37 Antibody (C-term) (AAA285487) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human testis tissue reacted with WDR37 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human testis tissue reacted with WDR37 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
WB (Western Blot)
(Western blot analysis of WDR37 Antibody (C-term) (AAA285487) in HepG2 cell line lysates (35ug/lane). WDR37 (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of WDR37 Antibody (C-term) (AAA285487) in HepG2 cell line lysates (35ug/lane). WDR37 (arrow) was detected using the purified Pab.)
Related Product Information for anti-WDR37 antibody
WDR37 encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes.
Product Categories/Family for anti-WDR37 antibody
References
Yoshida,T.,Int. J. Mol. Med. 25 (4), 649-656 (2010)
Deloukas,P., et.al, Nature 429 (6990), 375-381 (2004)
Deloukas,P., et.al, Nature 429 (6990), 375-381 (2004)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
54665
NCBI Official Full Name
WD repeat-containing protein 37
NCBI Official Synonym Full Names
WD repeat domain 37
NCBI Official Symbol
WDR37
NCBI Protein Information
WD repeat-containing protein 37
UniProt Protein Name
WD repeat-containing protein 37
UniProt Gene Name
WDR37
UniProt Synonym Gene Names
KIAA0982
UniProt Entry Name
WDR37_HUMAN
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Product Notes
The WDR37 wdr37 (Catalog #AAA285487) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 426-455. The WDR37 Antibody (C-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's WDR37 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the WDR37 wdr37 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "WDR37, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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