IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human placenta using AAA119874 at dilution 1:100)
Rabbit anti-Human, Mouse WIPI1 Polyclonal Antibody | anti-WIPI1 antibody
Rabbit anti-human WIPI1 polyclonal Antibody
Gene Names
WIPI1; ATG18; ATG18A; WIPI49
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Antigen Affinity Purified
Synonyms
WIPI1, Antibody; Rabbit anti-human WIPI1 polyclonal Antibody; WIPI-1; Atg18 protein homolog; WD40 repeat protein interacting with phosphoinositides of 49 kDa; WIPI 49 kDa; WIPI1; WIPI49; anti-WIPI1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
446
Applicable Applications for anti-WIPI1 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human WD repeat domain phosphoinositide-interacting protein 1 protein (187-446aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-83064 / sc-83063 / sc-292635
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human placenta using AAA119874 at dilution 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human placenta using AAA119874 at dilution 1:100)
WB (Western Blot)
(All lanes: WIPI1 antibody at 6ug/mlLane 1:293T whole cell lysateLane 2:NIH3T3 whole celllysateLane 3:mouse skeletal muscleSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 49kDaObserved band size: 49kDa)
WB (Western Blot)
(All lanes: WIPI1 antibody at 6ug/mlLane 1:293T whole cell lysateLane 2:NIH3T3 whole celllysateLane 3:mouse skeletal muscleSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 49kDaObserved band size: 49kDa)
Related Product Information for anti-WIPI1 antibody
Plays an important role in autophagy and in particular starvation- and calcium-mediated autophagy, as well as in mitophagy. Functions upstream of the ATG12-ATG5-ATG16L1 complex and LC3, and downstream of the ULK1 and PI3-kinase complexes. Involved in xenophagy of Staphylococcus aureus. Invading S.aureus cells become entrapped in autophagosome-like WIPI1 positive vesicles targeted for lysosomal degradation. Plays also a distinct role in controlling the transcription of melanogenic enzymes and melanosome maturation, a process that is distinct from starvation-induced autophagy. May also regulate the trafficking of proteins involved in the mannose-6-phosphate receptor (MPR) recycling pathway.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
48,202 Da
NCBI Official Full Name
WD repeat domain phosphoinositide-interacting protein 1
NCBI Official Synonym Full Names
WD repeat domain, phosphoinositide interacting 1
NCBI Official Symbol
WIPI1
NCBI Official Synonym Symbols
ATG18; ATG18A; WIPI49
NCBI Protein Information
WD repeat domain phosphoinositide-interacting protein 1
UniProt Protein Name
WD repeat domain phosphoinositide-interacting protein 1
UniProt Gene Name
WIPI1
UniProt Synonym Gene Names
WIPI49; WIPI-1; WIPI 49 kDa
UniProt Entry Name
WIPI1_HUMAN
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Product Notes
The WIPI1 wipi1 (Catalog #AAA119874) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human WIPI1 polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's WIPI1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the WIPI1 wipi1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "WIPI1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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