IHC (Immunohiostchemistry)
(Immunohistochemistry of WNT5 in rat colon tissue with WNT5 antibody at 5 μg/mL.)
Rabbit WNT5 Polyclonal Antibody | anti-WNT5 antibody
WNT5 Antibody
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
WNT5 antibody is affinity chromatography purified via peptide column.
Synonyms
WNT5, Antibody; WNT5 Antibody; Wingless-type MMTV integration site family member 5; wingless-type MMTV integration site family, member 5B; anti-WNT5 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
WNT5 antibody is human, mouse and rat reactive. WNT5 antibody will detect both WNT5A and WNT5B. At least two isoforms of WNT5B are known to exist; this antibody will detect both isoforms.
Purity/Purification
WNT5 antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
359
Applicable Applications for anti-WNT5 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
WNT5 antibody was raised against a 15 amino acid peptide near the center of human WNT5B.
Buffer
WNT5 antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
WNT5 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
IHC (Immunohiostchemistry)
(Immunohistochemistry of WNT5 in rat colon tissue with WNT5 antibody at 5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of WNT5 in rat colon tissue with WNT5 antibody at 5 μg/mL.)
WB (Western Blot)
(Western blot analysis of WNT5 in Jurkat cell lysate with WNT5 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
WB (Western Blot)
(Western blot analysis of WNT5 in Jurkat cell lysate with WNT5 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
Related Product Information for anti-WNT5 antibody
WNT5A and WNT5B are near-identical members of the WNT gene family, which consists of structurally related genes which encode secreted signaling proteins that have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis (1,2). WNT5A and WNT5B coordinate chondrocyte proliferation and differentiation by differentially regulating cyclin D1 and p130 expression, as well as chondrocyte-specific Col2a1 expression (3). Up-regulation of WNT5A and WNT5B has been observed in several types of human cancers, suggesting that they may be useful as markers or potent therapeutic targets (4).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 39 kDa
Observed: 465 kDa
Observed: 465 kDa
NCBI Official Full Name
protein Wnt-5b
NCBI Official Synonym Full Names
wingless-type MMTV integration site family, member 5B
NCBI Official Symbol
WNT5B
NCBI Protein Information
protein Wnt-5b; WNT-5B protein
UniProt Protein Name
Protein Wnt-5b
UniProt Gene Name
WNT5B
UniProt Entry Name
WNT5B_HUMAN
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Product Notes
The WNT5 wnt5b (Catalog #AAA40533) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The WNT5 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's WNT5 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the WNT5 wnt5b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "WNT5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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