ICC (Immunocytochemistry)
(Immunocytochemistry of XBP-1 in HepG2 cells with XBP-1 antibody at 2 μg/mL.)
Rabbit XBP-1 Polyclonal Antibody | anti-XBP1 antibody
XBP-1 Antibody
Gene Names
XBP1; XBP2; TREB5; XBP-1
Reactivity
Human, Mouse, Rat
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
XBP-1 Antibody is affinity chromatography purified via peptide column.
Synonyms
XBP-1, Antibody; XBP-1 Antibody; XBP-1; XBP2; TREB5; X-box-binding protein 1; Tax-responsive element-binding protein 5; X-box binding protein 1; anti-XBP1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
XBP-1 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
261
Applicable Applications for anti-XBP1 antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
XBP-1 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human XBP-1.
Buffer
XBP-1 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
XBP-1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry of XBP-1 in HepG2 cells with XBP-1 antibody at 2 μg/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of XBP-1 in HepG2 cells with XBP-1 antibody at 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of XBP-1 in PC-3 cell lysate with XBP-1 antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of XBP-1 in PC-3 cell lysate with XBP-1 antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL.)
Related Product Information for anti-XBP1 antibody
XBP-1 Antibody: X box binding protein 1 (XBP-1) is a key protein in the mammalian unfolded protein response (UPR) that protects the cell against the stress of malfolded proteins in the endoplasmic reticulum (ER). Upon sensing unfolded proteins, an ER transmembrane endonuclease and kinase termed IRE1p is activated and excises an intron from XBP-1 mRNA. The spliced XBP-1 mRNA results in a 371 amino acid protein (XBP-1s) which is then translocated to the nucleus where it binds to the regulatory elements of downstream genes. Together with other UPR transcription factors such as ATF6, XBP-1 stimulates the production of ER stress proteins including the ER resident protein chaperones glucose regulated protein (GRP) 78 and GRP94.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
40,148 Da
NCBI Official Full Name
X-box-binding protein 1
NCBI Official Synonym Full Names
X-box binding protein 1
NCBI Official Symbol
XBP1
NCBI Official Synonym Symbols
XBP2; TREB5; XBP-1
NCBI Protein Information
X-box-binding protein 1; tax-responsive element-binding protein 5
UniProt Protein Name
X-box-binding protein 1
UniProt Gene Name
XBP1
UniProt Synonym Gene Names
TREB5; XBP2; XBP-1
UniProt Entry Name
XBP1_HUMAN
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Product Notes
The XBP1 xbp1 (Catalog #AAA40114) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The XBP-1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's XBP-1 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the XBP1 xbp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "XBP-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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