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product-image-AAA302567_WB11.jpg WB (Western Blot) (Western blot analysis of extracts from COS7 cells (Lane 2), using XPA antiobdy. The lane on the left is treated with systhesized peptide.)

Rabbit anti-Human XPA Polyclonal Antibody | anti-XPA antibody

XPA Antibody

Gene Names
XPA; XP1; XPAC
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
XPA, Antibody; XPA Antibody; DNA-repair protein complementing XP-A cells; XPAC; Xeroderma pigmentosum group A complementing protein; anti-XPA antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total XPA protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
273
Applicable Applications for anti-XPA antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from Internal of human XPA.
Target Name
XPA
Preparation and Storage
Store at -20 degree C

WB (Western Blot)

(Western blot analysis of extracts from COS7 cells (Lane 2), using XPA antiobdy. The lane on the left is treated with systhesized peptide.)

product-image-AAA302567_WB11.jpg WB (Western Blot) (Western blot analysis of extracts from COS7 cells (Lane 2), using XPA antiobdy. The lane on the left is treated with systhesized peptide.)

WB (Western Blot)

(Western blot analysis of extracts from COLO205 cells, using XPA antibody.)

product-image-AAA302567_WB13.jpg WB (Western Blot) (Western blot analysis of extracts from COLO205 cells, using XPA antibody.)

IHC (Immunohistochemistry)

(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using XPA antibody.)

product-image-AAA302567_IHC15.jpg IHC (Immunohistochemistry) (Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using XPA antibody.)
Related Product Information for anti-XPA antibody
Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.Gary W. Daughdrill, Nucleic Acids Res., Jul 2003; 31: 4176 - 4183. Esther M. Hoogervorst, Carcinogenesis, Mar 2003; 24: 613 - 619. Karen M. Vasquez, PNAS, Apr 2002; 99: 5848.
Product Categories/Family for anti-XPA antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
31,368 Da
NCBI Official Full Name
DNA repair protein complementing XP-A cells
NCBI Official Synonym Full Names
xeroderma pigmentosum, complementation group A
NCBI Official Symbol
XPA
NCBI Official Synonym Symbols
XP1; XPAC
NCBI Protein Information
DNA repair protein complementing XP-A cells
UniProt Protein Name
DNA repair protein complementing XP-A cells
UniProt Gene Name
XPA
UniProt Synonym Gene Names
XPAC
UniProt Entry Name
XPA_HUMAN

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Product Notes

The XPA xpa (Catalog #AAA302567) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The XPA Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's XPA can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the XPA xpa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "XPA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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