IHC (Immunohiostchemistry)
(Anti-XRCC3 antibody, AAA45018, IHC(P)IHC(P): Rat Brain Tissue)
Rabbit anti-Mouse, Rat XRCC3 Polyclonal Antibody | anti-XRCC3 antibody
Anti-XRCC3 antibody
Gene Names
Xrcc3; AI182522; AW537713; 4432412E01Rik
Reactivity
Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
XRCC3, Antibody; Anti-XRCC3 antibody; DNA repair protein XRCC3; X-ray repair complementing defective repair in Chinese hamster cells 3; CMM6 antibody; DNA repair protein XRCC3 antibody; RAD51 like antibody; X ray repair complementing defective repair in Chinese hamster antibody; X ray repair complementing defective repair in Chinese hamster cells 3 antibody; X ray repair cross complementing protein 3 antibody; X-ray repair cross-complementing protein 3 antibody; XRCC 3 antibody; XRCC3 antibody; XRCC3_HUMAN antibody; anti-XRCC3 antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
349
Applicable Applications for anti-XRCC3 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of mouse XRCC3 (290-305aa NQLLMRLMVDRTHEDD), identical to the related rat sequence.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohiostchemistry)
(Anti-XRCC3 antibody, AAA45018, IHC(P)IHC(P): Rat Brain Tissue)
IHC (Immunohiostchemistry)
(Anti-XRCC3 antibody, AAA45018, IHC(P)IHC(P): Rat Brain Tissue)
WB (Western Blot)
(Anti-XRCC3 antibody, AAA45018, Western blottingAll lanes: Anti XRCC3(AAA45018) at 0.5ug/mlWB: Mouse Brain Tissue Lysate at 50ugPredicted bind size: 38KDObserved bind size: 38KD)
WB (Western Blot)
(Anti-XRCC3 antibody, AAA45018, Western blottingAll lanes: Anti XRCC3(AAA45018) at 0.5ug/mlWB: Mouse Brain Tissue Lysate at 50ugPredicted bind size: 38KDObserved bind size: 38KD)
Related Product Information for anti-XRCC3 antibody
Description: Rabbit IgG polyclonal antibody for DNA repair protein XRCC3(XRCC3) detection. Tested with WB, IHC-P in Mouse, Rat.
Background: XRCC3(X-RAY REPAIR, COMPLEMENTING DEFECTIVE, IN CHINESE HAMSTER, 3) is a DNA repair protein that in humans, is encoded by the XRCC3 gene. The XRCC3 is a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. XRCC3 interacts directly with RAD51 and may cooperate with RAD51 during recombinational repair. XRCC3 function is not limited to HR initiation, but extends to later stages in formation and resolution of HR intermediates, possibly by stabilizing heteroduplex DNA. The gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Background: XRCC3(X-RAY REPAIR, COMPLEMENTING DEFECTIVE, IN CHINESE HAMSTER, 3) is a DNA repair protein that in humans, is encoded by the XRCC3 gene. The XRCC3 is a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. XRCC3 interacts directly with RAD51 and may cooperate with RAD51 during recombinational repair. XRCC3 function is not limited to HR initiation, but extends to later stages in formation and resolution of HR intermediates, possibly by stabilizing heteroduplex DNA. The gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
38,446 Da
NCBI Official Full Name
DNA repair protein XRCC3
NCBI Official Synonym Full Names
X-ray repair complementing defective repair in Chinese hamster cells 3
NCBI Official Symbol
Xrcc3
NCBI Official Synonym Symbols
AI182522; AW537713; 4432412E01Rik
NCBI Protein Information
DNA repair protein XRCC3; X-ray repair cross-complementing protein 3
UniProt Protein Name
DNA repair protein XRCC3
UniProt Gene Name
Xrcc3
UniProt Entry Name
XRCC3_MOUSE
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Product Notes
The XRCC3 xrcc3 (Catalog #AAA45018) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-XRCC3 antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's XRCC3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the XRCC3 xrcc3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "XRCC3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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