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product-image-AAA286533_FCM13.jpg FCM/FACS (Flow Cytometry) (YLAT2 Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Rabbit anti-Human YLAT2 Polyclonal Antibody | anti-SLC7A6 antibody

YLAT2 Antibody (C-term)

Gene Names
SLC7A6; LAT3; LAT-2; y+LAT-2
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
YLAT2, Antibody; YLAT2 Antibody (C-term); Y+L amino acid transporter 2; Cationic amino acid transporter; y+ system; Solute carrier family 7 member 6; y(+)L-type amino acid transporter 2; Y+LAT2; y+LAT-2; SLC7A6 HGNC:11064); anti-SLC7A6 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This YLAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-515 amino acids from the C-terminal region of human YLAT2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
487-515
Sequence Length
515
Applicable Applications for anti-SLC7A6 antibody
FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

FCM/FACS (Flow Cytometry)

(YLAT2 Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

product-image-AAA286533_FCM13.jpg FCM/FACS (Flow Cytometry) (YLAT2 Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

WB (Western Blot)

(Western blot analysis of YLAT2 Antibody (C-term) in HepG2 cell line lysates (35ug/lane).YLAT2 (arrow) was detected using the purified Pab.)

product-image-AAA286533_WB15.jpg WB (Western Blot) (Western blot analysis of YLAT2 Antibody (C-term) in HepG2 cell line lysates (35ug/lane).YLAT2 (arrow) was detected using the purified Pab.)
Related Product Information for anti-SLC7A6 antibody
This protein involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. It requires co-expression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. It also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. It plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. It involved in the transport of L-arginine in monocytes and reduces uptake of ornithine in retinal pigment epithelial (RPE) cells.
Product Categories/Family for anti-SLC7A6 antibody
References
Sekine, Y., et al. J. Am. Soc. Nephrol. 20(7):1586-1596(2009)
Broer, S. Physiol. Rev. 88(1):249-286(2008)
Xu, D., et al. Mol. Cell Proteomics 4(8):1061-1071(2005)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
56828
NCBI Official Full Name
Y+L amino acid transporter 2
NCBI Official Synonym Full Names
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
NCBI Official Symbol
SLC7A6
NCBI Official Synonym Symbols
LAT3; LAT-2; y+LAT-2
NCBI Protein Information
Y+L amino acid transporter 2
UniProt Protein Name
Y+L amino acid transporter 2
UniProt Gene Name
SLC7A6
UniProt Synonym Gene Names
Y+LAT2; y+LAT-2
UniProt Entry Name
YLAT2_HUMAN

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Product Notes

The SLC7A6 slc7a6 (Catalog #AAA286533) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 487-515. The YLAT2 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's YLAT2 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the SLC7A6 slc7a6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "YLAT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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