IF (Immunofluorescence)
(Immunofluorescence of ZF21 in human kidney tissue with ZF21 antibody at 20 μg/mL.)
Rabbit ZF21 Polyclonal Antibody | anti-ZFYVE21 antibody
ZF21 Antibody
Gene Names
ZFYVE21; ZF21
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Western Blot, ELISA
Purity
ZF21 Antibody is affinity chromatography purified via peptide column.
Synonyms
ZF21, Antibody; ZF21 Antibody; ZF21; Zinc finger FYVE domain-containing protein 21; zinc finger, FYVE domain containing 21; anti-ZFYVE21 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
At least two isoforms of ZF21 are known to exist; this antibody will detect both isoforms.
Purity/Purification
ZF21 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
252
Applicable Applications for anti-ZFYVE21 antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
ZF21 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human ZF21.
Buffer
ZF21 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
ZF21 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of ZF21 in human kidney tissue with ZF21 antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of ZF21 in human kidney tissue with ZF21 antibody at 20 μg/mL.)
WB (Western Blot)
(Western blot analysis of ZF21 in 3T3 cell tissue lysate with ZF21 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
WB (Western Blot)
(Western blot analysis of ZF21 in 3T3 cell tissue lysate with ZF21 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)
Related Product Information for anti-ZFYVE21 antibody
ZF21 Antibody: ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
28,477 Da
NCBI Official Full Name
zinc finger FYVE domain-containing protein 21 isoform 1
NCBI Official Synonym Full Names
zinc finger, FYVE domain containing 21
NCBI Official Symbol
ZFYVE21
NCBI Official Synonym Symbols
ZF21
NCBI Protein Information
zinc finger FYVE domain-containing protein 21; FYVE domain containing 21
UniProt Protein Name
Zinc finger FYVE domain-containing protein 21
UniProt Gene Name
ZFYVE21
UniProt Synonym Gene Names
ZF21
UniProt Entry Name
ZFY21_HUMAN
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Product Notes
The ZFYVE21 zfyve21 (Catalog #AAA39959) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZF21 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ZF21 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the ZFYVE21 zfyve21 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZF21, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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