WB (Western Blot)
(ZFYVE27 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ZFYVE27 antibody detected the ZFYVE27 protein (arrow).)
Rabbit ZFYVE27 Polyclonal Antibody | anti-ZFYVE27 antibody
ZFYVE27 Antibody (N-term)
Gene Names
ZFYVE27; SPG33; PROTRUDIN
Reactivity
Human (Predicted Reactivity: Mouse, Rat)
Applications
ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
ZFYVE27, Antibody; ZFYVE27 Antibody (N-term); Protrudin; Zinc finger FYVE domain-containing protein 27; ZFYVE27; anti-ZFYVE27 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This ZFYVE27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the N-terminal region of human ZFYVE27.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
28-56
Sequence Length
372
Applicable Applications for anti-ZFYVE27 antibody
ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Primary Accession
Q5T4F4
Other Accession
Q6P7B7, Q3TXX3, NP_001002261.1, NP_001002262.1
Antigen Source
HUMAN
Function
Functions as an upstream inhibitor of RAB11, regulating directional protein transport to the forming neurites. Involved in nerve growth factor-induced neurite formation. May have a more general role in cell projections formation.
Cellular Location
Recycling endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell projection, growth cone membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein Note=Localizes at both dendrites and axons.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(ZFYVE27 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ZFYVE27 antibody detected the ZFYVE27 protein (arrow).)
WB (Western Blot)
(ZFYVE27 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ZFYVE27 antibody detected the ZFYVE27 protein (arrow).)
Related Product Information for anti-ZFYVE27 antibody
This gene encodes a protein with several transmembrane
domains, a Rab11-binding domain and a lipid-binding FYVE finger
domain. The encoded protein appears to promote neurite formation. A
mutation in this gene has been reported to be associated with
hereditary spastic paraplegia, however the pathogenicity of the
mutation, which may simply represent a polymorphism, is unclear.
domains, a Rab11-binding domain and a lipid-binding FYVE finger
domain. The encoded protein appears to promote neurite formation. A
mutation in this gene has been reported to be associated with
hereditary spastic paraplegia, however the pathogenicity of the
mutation, which may simply represent a polymorphism, is unclear.
Product Categories/Family for anti-ZFYVE27 antibody
References
Saita, S., et al. J. Biol. Chem. 284(20):13766-13777(2009)
Martignoni, M., et al. Am. J. Hum. Genet. 83(1):127-128(2008)
Shirane, M., et al. Science 314(5800):818-821(2006)
Mannan, A.U., et al. Am. J. Hum. Genet. 79(2):351-357(2006)
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
Martignoni, M., et al. Am. J. Hum. Genet. 83(1):127-128(2008)
Shirane, M., et al. Science 314(5800):818-821(2006)
Mannan, A.U., et al. Am. J. Hum. Genet. 79(2):351-357(2006)
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
45843
NCBI Official Full Name
protrudin isoform a
NCBI Official Synonym Full Names
zinc finger, FYVE domain containing 27
NCBI Official Symbol
ZFYVE27
NCBI Official Synonym Symbols
SPG33; PROTRUDIN
NCBI Protein Information
protrudin
UniProt Protein Name
Protrudin
UniProt Gene Name
ZFYVE27
UniProt Entry Name
ZFY27_HUMAN
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Product Notes
The ZFYVE27 zfyve27 (Catalog #AAA290153) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 28-56. The ZFYVE27 Antibody (N-term) reacts with Human (Predicted Reactivity: Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's ZFYVE27 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the ZFYVE27 zfyve27 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZFYVE27, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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