Rabbit anti-Human ZIMP10 Polyclonal Antibody | anti-ZMIZ1 antibody

ZIMP10 Antibody

Cat. Num. AAA40054

• Gene Names: ZMIZ1; MIZ; RAI17; ZIMP10; hZIMP10; TRAFIP10
• Reactivity: Human
• Applications: Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
• Purity: ZIMP10 Antibody is affinity chromatography purified via peptide column.
• Synonyms: ZIMP10, Antibody; ZIMP10 Antibody; ZIMP10; MIZ; RAI17; hZIMP10; TRAFIP10; KIAA1224; Zinc finger MIZ domain-containing protein 1; PIAS-like protein Zimp10; zinc finger, MIZ-type containing 1; anti-ZMIZ1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: At least three isoforms are known to exist; this antibody will recognize all three. ZIMP10 antibody is predicted to not cross-react with other PIAS protein family members.
• Purity/Purification: ZIMP10 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 1067

• Applicable Applications for anti-ZMIZ1 antibody: IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: ZIMP10 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human ZIMP10.
• Buffer: ZIMP10 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: ZIMP10 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of ZIMP10 in K562 cells with ZIMP10 antibody at 20 μg/mL.)

ICC (Immunocytochemistry)

(Immunocytochemistry of ZIMP10 in K562 cells with ZIMP10 antibody at 10 μg/mL.)

WB (Western Blot)

(Western blot analysis of ZIMP10 in K562 cell lysate with ZIMP10 antibody at 0.5 μg/mL in (A) the absence and (B) the presence of blocking peptide)

Related Product Information for anti-ZMIZ1 antibody

ZIMP10 Antibody: ZIMP10, also known as ZMIZ1, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein initially identified as a transcriptional co-activator of the androgen receptor (AR). ZIMP10 and the related protein ZIMP7 interact with PIAS3 and enhances AR-mediated transcription. Later experiments showed that ZIMP10 is also a co-activator of the p53 tumor suppressor. Mice deficient in ZIMP10 result in embryonic lethality by E10.5; these embryos reveal severe defects in the reorganization of the yolk sac vascular plexus, indicating that ZIMP10 plays an important role in proper vascular development.

NCBI and Uniprot Product Information

• NCBI GI #: 31543543
• NCBI GeneID: 57178
• NCBI Accession #: NP_65071
• NCBI GenBank Nucleotide #: NM_020338.3
• UniProt Accession #: Q9ULJ6; Q5JSH9; Q7Z7E6
• Molecular Weight: 107,270 Da
• NCBI Official Full Name: zinc finger MIZ domain-containing protein 1
• NCBI Official Synonym Full Names: zinc finger, MIZ-type containing 1
• NCBI Official Symbol: ZMIZ1
• NCBI Official Synonym Symbols: MIZ; RAI17; ZIMP10; hZIMP10; TRAFIP10
• NCBI Protein Information: zinc finger MIZ domain-containing protein 1; RP11-519K18.1; FLJ00092 protein; retinoic acid induced 17; zinc finger-containing, Miz1, PIAS-like protein on chromosome 10
• UniProt Protein Name: Zinc finger MIZ domain-containing protein 1
• UniProt Gene Name: ZMIZ1
• UniProt Synonym Gene Names: KIAA1224; RAI17; ZIMP10
• UniProt Entry Name: ZMIZ1_HUMAN