Rabbit anti-Human, Mouse ZIP12 Polyclonal Antibody | anti-Slc39a12 antibody

ZIP12 Antibody

Cat. Num. AAA40060

• Gene Names: SLC39A12; ZIP-12; LZT-Hs8; bA570F3.1
• Reactivity: Human, Mouse
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: ZIP12 Antibody is affinity chromatography purified via peptide column.
• Synonyms: ZIP12, Antibody; ZIP12 Antibody; ZIP12; ZIP-12; LZT-Hs8; bA570F3.1; Zinc transporter ZIP12; LIV-1 subfamily of ZIP zinc transporter 8; solute carrier family 39 (zinc transporter), member 12; anti-Slc39a12 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: At least four isoforms of ZIP12 are known to exist. ZIP12 antibody is predicted to not cross-react with other ZIP family members.
• Purity/Purification: ZIP12 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 691

• Applicable Applications for anti-Slc39a12 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: ZIP12 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human ZIP12.
• Buffer: ZIP12 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: ZIP12 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of ZIP12 in mouse liver tissue with ZIP12 antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of ZIP12 in mouse liver tissue with ZIP12 antibody at 2.5 μg/mL.)

WB (Western Blot)

(Western blot analysis of ZIP12 in HepG2 cell lysate with ZIP12 antibody at (A) 0.5 and (B) 1 μg/mL.)

Related Product Information for anti-Slc39a12 antibody

ZIP12 Antibody: The zinc transporter ZIP12, also known as SLC39A12, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP12 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Increased levels of ZIP12 have been observed during acute inflammation in the airway and asthma, suggesting that it may be promote increased zinc uptake, as this can reduce inflammation. The zinc content in brains in individuals with schizophrenia is lower than in individuals with other cerebral diseases, and mutations in ZIP12 have been observed in a small group of schizophrenic patients, suggesting that ZIP12 may play a role in this disease.

NCBI and Uniprot Product Information

• NCBI GI #: 223633939
• NCBI GeneID: 221074
• NCBI Accession #: NP_001138667
• NCBI GenBank Nucleotide #: NM_001145195.1
• UniProt Accession #: Q504Y0; Q49AN8; Q4G0L3; Q5VWV8; Q5VWV9; Q6NZY5; Q96NN4; B7ZL35; C9JJL4
• Molecular Weight: 76,538 Da
• NCBI Official Full Name: zinc transporter ZIP12 isoform 1
• NCBI Official Synonym Full Names: solute carrier family 39 (zinc transporter), member 12
• NCBI Official Symbol: SLC39A12
• NCBI Official Synonym Symbols: ZIP-12; LZT-Hs8; bA570F3.1
• NCBI Protein Information: zinc transporter ZIP12; zrt- and Irt-like protein 12; solute carrier family 39 member 12; LIV-1 subfamily of ZIP zinc transporter 8; solute carrier family 39 (metal ion transporter), member 12
• UniProt Protein Name: Zinc transporter ZIP12
• UniProt Gene Name: SLC39A12
• UniProt Synonym Gene Names: ZIP12; LZT-Hs8; ZIP-12
• UniProt Entry Name: S39AC_HUMAN