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product-image-AAA75986_WB15.png WB (Western Blot)

SGLT1 positive control

SGLT1 Positive Control

Gene Names
SLC5A1; NAGT; SGLT1; D22S675
Applications
Western Blot
Synonyms
SGLT1; N/A; SGLT1 Positive Control; D22S675; High affinity sodium glucose cotransporter 1; Human Na+/glucose cotransporter 1; NAGT; SGLT 1; SLC5A1; Sodium glucose cotransporter 1; Solute carrier family 5 member 1 antibody; SGLT1 positive control
Ordering
Form/Format
Western Blot Positive Control in ready to use SDS-sample buffer
Applicable Applications for SGLT1 positive control
WB (Western Blot)
Immunogen
Purified Protein
Preparation and Storage
Store at -20°C for long term storage

WB (Western Blot)

product-image-AAA75986_WB15.png WB (Western Blot)
Related Product Information for SGLT1 positive control
Western Blot Positive Control Sodum/glucose cotransporter 1
Sodium-glucose linked transporters (SGL T) are a family of glucose tranporters that contribute to renal glucose reabsorption. The two most common members of SGL T family are members of the SLC5A gene family: SGL T1 and SGL T2. There are five other members in the human protein family SLC5A, which may also be sodium-glucose transporters (1). SGL Ts utilize secondary active transport to transport glucose along kidney proximal tubules by sodium ion cotransport with a sodium ion to glucose coupling ration of 2:1. A Na+/K+ ATPase pump on the basolateral membrane of the proximal tubules cells utilizes ATP to move 3 Sodium ions outward into the blood, and 2 potassium ions into the cell. The energy from the resulting downhill sodium ion gradient is utilized by SGL Ts to transport glucose across the apical membrane. Since sodium and glucose are transported in the same direction, SGL Ts are classified as symporters. SGL Ts are mainly expressed in intestine and kidney. SGL T and GLUT antibodies have been fully characterized for cross reactivity within the SGL T and GLUT families and also with other cellular proteins. Antibodies against multiple epitopes on the same protein to facilitate studies using interspecies cross reactivity. SGL T western blot positive control (PC-SGL T) is available in read-to-use SOS-PAGE sample buffer. The SGL T positive control appears as a diffuse band of 69-72 and co-migrates with rat jejune.1 sodium-dependent glucose transporter protein on a 10% SOS-PAGE.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
sodium/glucose cotransporter 1 isoform 1
NCBI Official Synonym Full Names
solute carrier family 5 member 1
NCBI Official Symbol
SLC5A1
NCBI Official Synonym Symbols
NAGT; SGLT1; D22S675
NCBI Protein Information
sodium/glucose cotransporter 1
UniProt Protein Name
Sodium/glucose cotransporter 1
UniProt Gene Name
SLC5A1
UniProt Synonym Gene Names
NAGT; SGLT1; Na(+)/glucose cotransporter 1
UniProt Entry Name
SC5A1_HUMAN

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Product Notes

The SGLT1 slc5a1 (Catalog #AAA75986) is a Positive Control and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's SGLT1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the SGLT1 slc5a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SGLT1, Positive Control" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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