SDS-PAGE
Gankyrin Recombinant Protein | PSMD10 recombinant protein
Gankyrin, 1-226aa, Human,E Coli
Gene Names
PSMD10; p28; p28(GANK); dJ889N15.2
Applications
SDS-Page
Purity
> 95% by SDS-PAGE
Synonyms
Gankyrin; N/A; Gankyrin, 1-226aa, Human,E Coli; proteasome 26S subunit non ATPase 10 (PSMD10) isoform 1; ankyrin repeat protein p28; 26S proteasome non-ATPase regulatory subunit 10; 26S proteasome regulatory subunit p28; PSMD10.; PSMD10 recombinant protein
Host
E Coli
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid in phosphate buffered saline (pH 7.4), 10% glycerol
Concentration
1 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MEGCVSNLMV CNLAYSGKLE ELKESILADK SLATRTDQDS RTALHWACSA GHTEIVEFLL QLGVPVNDKD DAGWSPLHIA ASAGRDEIVK ALLGKGAQVN AVNQNGCTPL HYAASKNRHE IAVMLLEGGA NPDAKDHYEA TAMHRAAAKG NLKMIHILLY YKASTNIQDT EGNTPLHLAC DEERVEEAKL LVSQGASIYI ENKEEKTPLQ VAKGGLGLIL KRMVEG
Sequence Length
226
Applicable Applications for PSMD10 recombinant protein
SDS-PAGE
Preparation and Storage
Can be stored at 4°C short term (1-2 weeks).
For long term storage, aliquot and store at -20°C or -70° C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20°C or -70° C.
Avoid repeated freezing and thawing cycles.
SDS-PAGE
SDS-PAGE
Related Product Information for PSMD10 recombinant protein
Gankyrin is an oncoprotein commonly overexpressed in most hepatocellular carcinomas. Gankyrin interacts with S6 ATPase of the 19S regulatory particle of the 26S proteasome. It is known to play a role in the regulation of the phosphorylation of the retinoblastoma protein by CDK4, and to enhance the ubiquitinylation of p53 by MDM2. Gankyrin consists of 7 ankyrin repeats and is structurally similar to I kappa Bs. Recombinant human Gankyrin was expressed in E Coli and purified by conventional chromatography techniques.
Product Categories/Family for PSMD10 recombinant protein
References
umemura A., et al. (2008) Hepatology. 47 (2):493-502.; Chen Y., et al. (2007) Cell Res. 17 (12): 1020-9;
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
24.4kDa (226aa), confirmed by MALDI-TOF.
NCBI Official Full Name
26S proteasome non-ATPase regulatory subunit 10 isoform 1
NCBI Official Synonym Full Names
proteasome 26S subunit, non-ATPase 10
NCBI Official Symbol
PSMD10
NCBI Official Synonym Symbols
p28; p28(GANK); dJ889N15.2
NCBI Protein Information
26S proteasome non-ATPase regulatory subunit 10
UniProt Protein Name
26S proteasome non-ATPase regulatory subunit 10
UniProt Gene Name
PSMD10
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Product Notes
The PSMD10 psmd10 (Catalog #AAA48512) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Gankyrin can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the PSMD10 psmd10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MEGCVSNLMV CNLAYSGKLE ELKESILADK SLATRTDQDS RTALHWACSA GHTEIVEFLL QLGVPVNDKD DAGWSPLHIA ASAGRDEIVK ALLGKGAQVN AVNQNGCTPL HYAASKNRHE IAVMLLEGGA NPDAKDHYEA TAMHRAAAKG NLKMIHILLY YKASTNIQDT EGNTPLHLAC DEERVEEAKL LVSQGASIYI ENKEEKTPLQ VAKGGLGLIL KRMVEG. It is sometimes possible for the material contained within the vial of "Gankyrin, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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