Application Data
Rabbit SOCS2 Antibody | anti-SOCS2 antibody
Rabbit anti SOCS-2 antibody
Gene Names
SOCS2; CIS2; SSI2; Cish2; SSI-2; SOCS-2; STATI2
Reactivity
Human, Mouse, Rat, Chicken, Bovine, Dog
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
The Rabbit IgG is purified by Epitope Affinity Purification.
Synonyms
SOCS2; N/A; Rabbit anti SOCS-2 antibody; Rabbit anti-SOCS-2; Suppressor of Cytokine Signaling 2 (SOCS2);; anti-SOCS2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat, Chicken, Bovine, Dog
Specificity
This antibody recognizes ~23 kDa of SOCS-2 protein from human and mouse origins. The other species are not tested.
Purity/Purification
The Rabbit IgG is purified by Epitope Affinity Purification.
Form/Format
This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer.
Concentration
Size: 100 ug/200 ul (varies by lot)
Applicable Applications for anti-SOCS2 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Antigen Preparation
A synthetic peptide corresponding to the C-terminus of SOCS-2 protein from human, mouse and rat origins.
Positive Control
Mouse muscle lysate
Preparation and Storage
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Application Data
Application Data
Related Product Information for anti-SOCS2 antibody
Cytokines induce a variety of biological responses by binding to specific cell surface receptors and activating cytoplasmic signal transduction pathways which are suppressed by other transcriptional factors. Proteins that mediate these signals from the cell surface to the nucleus include JAKs and STATs, while SOCS (Suppressor of cytokine signaling) proteins inhibit those signaling. The SOCS family comprises at least 8 members, SOCS1 to SOCS7 and CIS (cytokine inducible SH2 containing protein). Structurally, the SOCS proteins are composed of an N terminal region of variable length and amino acid composition, a central SH2 domain, and a previously unrecognized C terminal motif named the SOCS box. SOCS 2 is considered to regulate postnatal growth, such as GH/IGF-1 pathway.
References
Bhakta R. Dey, et al. Interaction of Human Suppressor of Cytokine Signaling (SOCS)-2 with the Insulin-like Growth Factor-I Receptor J. Biol. Chem., Sep 1998; 273: 24095 - 24101
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
23 kDa
NCBI Official Full Name
suppressor of cytokine signaling 2
NCBI Official Synonym Full Names
suppressor of cytokine signaling 2
NCBI Official Symbol
SOCS2
NCBI Official Synonym Symbols
CIS2; SSI2; Cish2; SSI-2; SOCS-2; STATI2
NCBI Protein Information
suppressor of cytokine signaling 2; CIS-2; STAT induced STAT inhibitor-2; STAT-induced STAT inhibitor 2; STAT-induced STAT inhibitor-2; cytokine-inducible SH2 protein 2; suppressor of cytokine signaling-2
UniProt Protein Name
Suppressor of cytokine signaling 2
UniProt Gene Name
SOCS2
UniProt Synonym Gene Names
CIS2; SSI2; STATI2
UniProt Entry Name
SOCS2_HUMAN
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Product Notes
The SOCS2 socs2 (Catalog #AAA71411) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti SOCS-2 antibody reacts with Human, Mouse, Rat, Chicken, Bovine, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's SOCS2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the SOCS2 socs2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SOCS2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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