WB (Western Blot)
(Western Blot: The whole cell lysate derived from HT-29 (lane 1), Mouse Liver (lane 2), mouse lung (lane 3) were immunoblotted by Rabbit anti-PCSK9 (Cat#AAA71426))
Rabbit PCSK9 Antibody | anti-PCSK9 antibody
Rabbit anti PCSK9 antibody
Gene Names
PCSK9; FH3; PC9; NARC1; LDLCQ1; NARC-1; HCHOLA3
Reactivity
Human, Rat, Mouse, Gorilla
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
The Rabbit IgG is purified by Epitope-Specific Affinity Purification.
Synonyms
PCSK9; N/A; Rabbit anti PCSK9 antibody; Rabbit anti-PCSK9; Proprotein convertase subtilisin/kexin type 9 (PCSK9) Proprotein concertase PC9; Subtilisin/Kexin-like protease PC9; FH3; NARC1; anti-PCSK9 antibody
Host
Rabbit
Reactivity
Human, Rat, Mouse, Gorilla
Specificity
This antibody recognizes ~74 kDa of human PCSK9 protein. It also reacts with mouse and rat. The other species are not tested.
Purity/Purification
The Rabbit IgG is purified by Epitope-Specific Affinity Purification.
Form/Format
This affinity purified antibody is supplied in sterile Phosphate-buffered saline (pH7.2) containing antibody stabilizer
Concentration
Size: 100 ug/200 ul (varies by lot)
Applicable Applications for anti-PCSK9 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Antigen Preparation
A synthetic peptide derived from 100aa-300aa of Human PCSK9 protein. This sequence is identical among human, rat, mouse, gorilla, etc.
Positive Control
HT-29, or mouse liver
Preparation and Storage
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
WB (Western Blot)
(Western Blot: The whole cell lysate derived from HT-29 (lane 1), Mouse Liver (lane 2), mouse lung (lane 3) were immunoblotted by Rabbit anti-PCSK9 (Cat#AAA71426))
WB (Western Blot)
(Western Blot: The whole cell lysate derived from HT-29 (lane 1), Mouse Liver (lane 2), mouse lung (lane 3) were immunoblotted by Rabbit anti-PCSK9 (Cat#AAA71426))
Related Product Information for anti-PCSK9 antibody
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a member of the serine protease family with a critical role in cholesterol metabolism by controlling the levels of low density lipoprotein (LDL) particles that circulate in the bloodstream. Mutation in the PCSK9 gene is associated with autosomal dominant hypercholesterolemia which is characterized by an increase in LDL cholesterol levels. PCSK9 is expressed in various tissues such as liver, kidney, lung, spleen, etc. Human PCSK9 precursor is 692 aa protein with 74kDa molecular weight. Its mature form has molecular weight ranging of 62-66 kDa in the tissues.
References
Lopez D (2008) PCSK9: an enigmatic protease. Biochim Biophys Acta. 1781 (4): 184-91.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
74 kDa or 64 kDa
NCBI Official Full Name
proprotein convertase subtilisin/kexin type 9 preproprotein
NCBI Official Synonym Full Names
proprotein convertase subtilisin/kexin type 9
NCBI Official Symbol
PCSK9
NCBI Official Synonym Symbols
FH3; PC9; NARC1; LDLCQ1; NARC-1; HCHOLA3
NCBI Protein Information
proprotein convertase subtilisin/kexin type 9; OTTHUMP00000009833; subtilisin/kexin-like protease PC9; neural apoptosis regulated convertase 1; convertase subtilisin/kexin type 9 preproprotein
UniProt Protein Name
Proprotein convertase subtilisin/kexin type 9
UniProt Gene Name
PCSK9
UniProt Synonym Gene Names
NARC1
UniProt Entry Name
PCSK9_HUMAN
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Product Notes
The PCSK9 pcsk9 (Catalog #AAA71426) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti PCSK9 antibody reacts with Human, Rat, Mouse, Gorilla and may cross-react with other species as described in the data sheet. AAA Biotech's PCSK9 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the PCSK9 pcsk9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PCSK9, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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