WB (Western Blot)
(Western blot analysis of COT phosphorylation expression in UV treated 293 whole cell lysates, The lane on the left is treated with the antigen-specific peptide.)
Rabbit COT Antibody | anti-COT antibody
Phospho-COT (Thr290) Antibody
Gene Names
MAP3K8; COT; EST; ESTF; TPL2; AURA2; MEKK8; Tpl-2; c-COT
Reactivity
Human, Mouse, Rat
Applications
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified
Synonyms
COT; N/A; Phospho-COT (Thr290) Antibody; EC 2.7.11.25; COT proto-oncogene serine/threonine-protein kinase; C-COT; Cancer Osaka thyroid oncogene; Tumor progression locus 2; TPL-2; anti-COT antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Isotype
IgG
Specificity
Phospho-COT (Thr290) Antibody detects endogenous levels of COT only when phosphorylated at Threonine 290
Purity/Purification
Immunogen affinity purified
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
467
Applicable Applications for anti-COT antibody
ICC (Immunocytochemistry), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthesized peptide derived from human COT around the phosphorylation site of Threonine 290
Preparation and Storage
Store at-20 degree C for 1 year
WB (Western Blot)
(Western blot analysis of COT phosphorylation expression in UV treated 293 whole cell lysates, The lane on the left is treated with the antigen-specific peptide.)
WB (Western Blot)
(Western blot analysis of COT phosphorylation expression in UV treated 293 whole cell lysates, The lane on the left is treated with the antigen-specific peptide.)
Related Product Information for anti-COT antibody
This gene was identified by its oncogenic transforming activity in cells. The encoded protein is a member of the serine/threonine protein kinase family. This kinase can activate both the MAP kinase and JNK kinase pathways.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
60kDa
NCBI Official Full Name
mitogen-activated protein kinase kinase kinase 8
NCBI Official Synonym Full Names
mitogen-activated protein kinase kinase kinase 8
NCBI Official Symbol
MAP3K8
NCBI Official Synonym Symbols
COT; EST; ESTF; TPL2; AURA2; MEKK8; Tpl-2; c-COT
NCBI Protein Information
mitogen-activated protein kinase kinase kinase 8
UniProt Protein Name
Mitogen-activated protein kinase kinase kinase 8
UniProt Gene Name
MAP3K8
UniProt Synonym Gene Names
COT; ESTF; TPL-2
Similar Products
Product Notes
The COT map3k8 (Catalog #AAA267881) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Phospho-COT (Thr290) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's COT can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the COT map3k8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COT, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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