IF (Immunofluorescence)
(Immunofluorescence staining of methanol-fixed HeLa cells using Phospho-PTK2B-Y402 antibody.)
Rabbit PTK2B-Y402 Antibody | anti-PTK2B antibody
Phospho-PTK2B-Y402 Polyclonal Antibody
Gene Names
PTK2B; PKB; PTK; CAKB; FAK2; PYK2; CADTK; FADK2; RAFTK
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Affinity Purification
Synonyms
PTK2B-Y402; N/A; Phospho-PTK2B-Y402 Polyclonal Antibody; Phospho-PTK2B-Y402: PKB; PTK; CAKB; FAK2; PYK2; CADTK; FADK2; RAFTK; anti-PTK2B antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Isotype
IgG
Purity/Purification
Affinity Purification
Concentration
1mg/ml (varies by lot)
Sequence Length
1009
Applicable Applications for anti-PTK2B antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Species
Human
Route
Synthetic Peptide
Immunogen
A phospho specific peptide corresponding to residues surrounding Y402 of human PTK2B
Calculated Molecular Weight
116kDa
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
IF (Immunofluorescence)
(Immunofluorescence staining of methanol-fixed HeLa cells using Phospho-PTK2B-Y402 antibody.)
IF (Immunofluorescence)
(Immunofluorescence staining of methanol-fixed HeLa cells using Phospho-PTK2B-Y402 antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human breast carcinoma using Phospho-PTK2B-Y402 antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human breast carcinoma using Phospho-PTK2B-Y402 antibody.)
WB (Western Blot)
(Western blot analysis of extracts from 293 cells, using Phospho-PTK2B-Y402 antibody.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% BSA.)
WB (Western Blot)
(Western blot analysis of extracts from 293 cells, using Phospho-PTK2B-Y402 antibody.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% BSA.)
Related Product Information for anti-PTK2B antibody
This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.
Product Categories/Family for anti-PTK2B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
3030
NCBI Official Full Name
Protein-tyrosine kinase 2-beta
NCBI Official Synonym Full Names
protein tyrosine kinase 2 beta
NCBI Official Symbol
PTK2B
NCBI Official Synonym Symbols
PKB; PTK; CAKB; FAK2; PYK2; CADTK; FADK2; RAFTK
NCBI Protein Information
protein-tyrosine kinase 2-beta; FADK 2; CAK-beta; protein kinase B; focal adhesion kinase 2; cell adhesion kinase beta; proline-rich tyrosine kinase 2; calcium-dependent tyrosine kinase; PTK2B protein tyrosine kinase 2 beta; related adhesion focal tyrosine kinase; calcium-regulated non-receptor proline-rich tyrosine kinase
UniProt Protein Name
Protein-tyrosine kinase 2-beta
UniProt Gene Name
PTK2B
UniProt Synonym Gene Names
FAK2; PYK2; RAFTK; CADTK; CAK-beta; CAKB; FADK 2; RAFTK
UniProt Entry Name
FAK2_HUMAN
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Product Notes
The PTK2B ptk2b (Catalog #AAA37344) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Phospho-PTK2B-Y402 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PTK2B-Y402 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the PTK2B ptk2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTK2B-Y402, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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