Rabbit anti-Human IL21R Antibody | anti-IL21R antibody
Rabbit anti Human IL21R Monoclonal Antibody
Gene Names
IL21R; NILR; CD360
Reactivity
Human
Applications
ELISA
Purity
Affinity purification
Synonyms
IL21R; N/A; Rabbit anti Human IL21R Monoclonal Antibody; anti-IL21R antibody
Host
Rabbit
Reactivity
Human
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
0.2um filtered solution in PBS
Applicable Applications for anti-IL21R antibody
ELISA
Immunogen
Recombinant Human IL21R
Note
Centrifuge before opening to ensure complete recovery of vial contents.
Preparation and Storage
Store at -20°C, avoid freeze/thaw cycles
Related Product Information for anti-IL21R antibody
Interleukin-21 receptor, also known as IL-21 receptor, IL-21R, Novel interleukin receptor, IL21R and NILR, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 4 subfamily. Interleukin-21 (IL-21) belongs to a family of cytokines that bind to a composite receptor consisting of a private receptor (IL-21R) and the common cytokine receptor gamma chain (gamma (C)). The IL-21R is discovered as a novel member of the class-I-cytokine-receptor family and is selectively expressed in lymphoid tissues. IL-21R shows strong sequence homologies to the interleukin-4 receptor alpha chain gene (IL-4RA). The WSXWS motif of IL-21R appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. The box 1 motif of IL-21R is required for JAK interaction and/or activation. The IL-21R is widely distributed on lympho-haematopoietic cells and IL21 impacts a number of cell types, including CD8+ memory T cells, NK cells and subsets of CD4 memory T cells. Increased IL21 production is characteristic of certain autoimmune diseases and is likely to contribute to autoantibody production as well as pathological features of autoimmune disease.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
IL21R
NCBI Official Synonym Full Names
interleukin 21 receptor
NCBI Official Symbol
IL21R
NCBI Official Synonym Symbols
NILR; CD360
NCBI Protein Information
interleukin-21 receptor
UniProt Protein Name
Interleukin-21 receptor
UniProt Gene Name
IL21R
UniProt Synonym Gene Names
NILR; IL-21 receptor; IL-21R
UniProt Entry Name
IL21R_HUMAN
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Product Notes
The IL21R il21r (Catalog #AAA173480) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Human IL21R Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL21R can be used in a range of immunoassay formats including, but not limited to, ELISA. Researchers should empirically determine the suitability of the IL21R il21r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL21R, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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