Standard Curve (Sample)
Rat DLL4 ELISA Kit | DLL4 elisa kit
Rat DLL4 ELISA Kit
Reactivity
Rat
Synonyms
DLL4; N/A; Rat DLL4 ELISA Kit; Delta-like protein 4; Drosophila Delta homolog 4; Delta4; DLL4 elisa kit
Reactivity
Rat
Specificity
The Rat DLL4 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Rat DLL4 proteins within the range of 15.6 pg/ml - 1000 pg/ml.
Sequence Length
686
Samples
Cell Culture Supernates, Serum, Plasma
Sensitivity
<10 pg/ml
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Standard Curve (Sample)
Standard Curve (Sample)
Related Product Information for DLL4 elisa kit
Principle of the Assay: The Rat DLL4 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Rat DLL4 in Cell Culture Supernates, Serum, Plasma. This assay employs an antibody specific for Rat DLL4 coated on a 96-well plate. Standards and samples are pipetted into the wells and DLL4 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Rat DLL4 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of DLL4 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.
Background: Delta like ligand 4 is a protein that in humans is encoded by the DLL4 gene. It is mapped to 15q15.1. This gene is a homolog of the Drosophila delta gene. DLL4 is a transmembrane ligand for Notch receptors that shows restricted expression to endothelial cells (ECs), in particular to arteries and capillaries, and is involved in vascular development, and it also appeared to be a major trigger of Notch receptor activities previously implicated in arterial and vascular development. DLL4 acts as a negative regulator of tumor angiogenesis, its blockade results in the striking uncoupling of tumor growth from vessel density, presenting a novel therapeutic approach even for tumors resistant to anti-VEGF therapies. In addition to it, this gene also plays an important role in promoting Th17 effector activity during mycobacterial challenge.
Background: Delta like ligand 4 is a protein that in humans is encoded by the DLL4 gene. It is mapped to 15q15.1. This gene is a homolog of the Drosophila delta gene. DLL4 is a transmembrane ligand for Notch receptors that shows restricted expression to endothelial cells (ECs), in particular to arteries and capillaries, and is involved in vascular development, and it also appeared to be a major trigger of Notch receptor activities previously implicated in arterial and vascular development. DLL4 acts as a negative regulator of tumor angiogenesis, its blockade results in the striking uncoupling of tumor growth from vessel density, presenting a novel therapeutic approach even for tumors resistant to anti-VEGF therapies. In addition to it, this gene also plays an important role in promoting Th17 effector activity during mycobacterial challenge.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
74,961 Da
NCBI Official Full Name
delta-like protein 4 isoform X1
NCBI Official Synonym Full Names
delta like canonical Notch ligand 4
NCBI Official Symbol
Dll4
NCBI Protein Information
delta-like protein 4
UniProt Protein Name
Delta-like protein 4
UniProt Gene Name
Dll4
UniProt Synonym Gene Names
Delta4Curated
UniProt Entry Name
DLL4_RAT
Similar Products
Product Notes
The Rat DLL4 dll4 (Catalog #AAA263160) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA263160 ELISA Kit recognizes Rat DLL4. It is sometimes possible for the material contained within the vial of "DLL4, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.