Penicillin-Streptomycin-Amphotericin B Reagent
Penicillin-Streptomycin-Amphotericin B solution (100x)
Synonyms
Penicillin-Streptomycin-Amphotericin B; N/A; Penicillin-Streptomycin-Amphotericin B solution (100x); Penicillin-Streptomycin-Amphotericin B reagent
Form/Format
Liquid. 10mM PBS (pH6.2)
Concentration
100x (varies by lot)
pH
6.1-6.4
Amphotericin B
25ug/mL
Dissolvent
10mM PBS (PH 6.2)
Streptomycin sulfate
10mg/mL
Penicillin G
10kU/mL
Preparation and Storage
Store at -20°C, shading light
Related Product Information for Penicillin-Streptomycin-Amphotericin B reagent
Background: Penicillin-streptomycin solution mixture is the most commonly used antibiotic to prevent microbial contamination in vitro. Penicillin can interfere with the synthesis of bacterial cell wall, especially for Gram-positive bacteria. Streptomycin could bind to ribosomal ribosome for 30S and inhibit the synthesis of bacterial protein. It was effective for Gram-negative bacteria and Gram-positive bacteria, but especially for Gram-negative bacteria. Amphotericin B can bind with ergosterol on the membrane of fungi, leading to damage of the membrane, improvement of permeability, leakage of substances inside the cell, disruption of normal metabolism and bacteriostatic effect, but no effect on bacteria. The combined use of penicillin, streptomycin & amphotericin B can prevent most bacterial and fungus contamination. But penicillin solution is sensitive to temperature and pH, easy to degrade at room temperature, and needs cryopreservation, the stability of penicillin solution is the most stable when pH is 6.0 - 6.5. Streptomycin was relatively stable, and pH 5.0-7.5 was the most stable. Amphotericin B solution is unstable at room temperature, easily destroyed by light, heat and acid, and has the strongest antibacterial effect at pH 6.0 - 7.5.
Product Categories/Family for Penicillin-Streptomycin-Amphotericin B reagent
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Product Notes
The Penicillin-Streptomycin-Amphotericin B (Catalog #AAA177036) is a Reagent and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Penicillin-Streptomycin-Amphotericin B, Reagent" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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