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product-image-AAA48449_SDS_PAGE15.jpg SDS-PAGE

RXR-alpha recombinant protein

RXR-alpha (Retinoid x receptor),111-228aa, Human, E Coli

Gene Names
RXRA; NR2B1
Applications
SDS-Page
Purity
> 95% by SDS-PAGE
Synonyms
RXR-alpha; N/A; RXR-alpha (Retinoid x receptor),111-228aa, Human, E Coli; Retinoid X receptor alpha; RXRA; NR2B1; Retinoid x receptor; Nuclear receptor subfamily 2 group B member 1; Retinoic acid receptor RXR-alpha; FLJ16020; FLJ16733; MGC102720; Retinoic acid receptor RXR alpha; RXR alpha1; RXRalpha1; RXRA1; RXR-alpha recombinant protein
Ordering
Host
E Coli
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl pH7.5, 0.1M NaCl, 5mM beta-Mercaptoethanol
Concentration
1 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MLGLNGVLKV PAHPSGNMAS FTKHICAICG DRSSGKHYGV YSCEGCKGFF KRTVRKDLTY TCRDNKDCLI DKRQRNRCQY CRYQKCLAMG MKREAVQEER QRGKDRNENE VESTSSANE
Sequence Length
462
Applicable Applications for RXR-alpha recombinant protein
SDS-PAGE
Antigen Species
Human
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.

SDS-PAGE

product-image-AAA48449_SDS_PAGE15.jpg SDS-PAGE
Related Product Information for RXR-alpha recombinant protein
The retinoid X receptor (RXR) is a pleiotropic nuclear receptor transcription factor that interacts with a variety of nuclear receptor dimeric partner. RXR binds cognate response elements as a homodimer in the presence of its ligand, 9-cis retinoic acid, or as a heterodimer with other members of the nuclear hormone receptor superfamily including retinoic acid receptors (RAR), thyroid hormone receptors (TR), vitamin D receptors and peroxisome proliferators-activated receptors (PPAR). The RXR family includes three difference isoforms ; RXR alpha, beta, gamma. Human RXR alpha gene is localized on 9q34.9 and encodes two major isoforms (RXR alpha1, RXR alpha2). The DNA binding domain of RXR (111-228aa) was over expressed in E Coli and purified by using conventional column chromatography techniques.
Product Categories/Family for RXR-alpha recombinant protein
References
Si J., et al. (2002) Blood, 100 (13);4401-9.; Zeng M., et al. (2002) J. Biol. Chem. 277 (47):45611-8.;

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
13.6 kDa (119 aa), confirmed by MALDI-TOF.
NCBI Official Full Name
retinoic acid receptor RXR-alpha isoform a
NCBI Official Synonym Full Names
retinoid X receptor alpha
NCBI Official Symbol
RXRA
NCBI Official Synonym Symbols
NR2B1
NCBI Protein Information
retinoic acid receptor RXR-alpha
UniProt Protein Name
Retinoic acid receptor RXR-alpha
UniProt Gene Name
RXRA
UniProt Synonym Gene Names
NR2B1

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Product Notes

The RXR-alpha rxra (Catalog #AAA48449) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's RXR-alpha can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the RXR-alpha rxra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MLGLNGVLKV PAHPSGNMAS FTKHICAICG DRSSGKHYGV YSCEGCKGFF KRTVRKDLTY TCRDNKDCLI DKRQRNRCQY CRYQKCLAMG MKREAVQEER QRGKDRNENE VESTSSANE. It is sometimes possible for the material contained within the vial of "RXR-alpha, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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