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product-image-AAA45277_SC15.jpg Standard Curve (Sample) (Human sL-Selectin PicoKine ELISA Kit standard curve)

Human sL-Selectin ELISA Kit | SELL elisa kit

Human sL-Selectin PicoKine ELISA Kit

Gene Names
SELL; TQ1; LAM1; LEU8; LNHR; LSEL; CD62L; LYAM1; PLNHR; LECAM1
Reactivity
Human
Synonyms
sL-Selectin; N/A; Human sL-Selectin PicoKine ELISA Kit; L-selectin; selectin L; A.11; AI528707; CD62 antigen ligand; CD62 antigen-like family member L; CD62L antigen; gp90 MEL; hLHRc; IgA nephropathy, susceptibility to, included; L Selectin; L selectin precursor; LAM 1; LAM1; LECAM1; Leu 8; Leu8; Leukocyte adhesion molecule 1; Leukocyte endothelial cell adhesion molecule 1; Leukocyte surface antigen Leu 8; Leukocyte surface antigen Leu8; Leukocyte-endothelial cell adhesion molecule 1; LNHR; LSEL; Ly-22; Ly-m22; Lyam 1; LYAM1; Lymph node homing receptor; Lymphocyte adhesion molecule 1; Lymphocyte antigen 22; Lymphocyte surface MEL-14 antigen; PLNHR; Selectin L; Selectin L (lymphocyte adhesion molecule 1); Selectin, lymphocyte; SELL; TQ1; SELL elisa kit
Ordering
Reactivity
Human
Specificity
Natural and recombinant human sL-Selectin
Sequence Length
372
Samples
Cell culture supernates, serum and plasma (heparin, EDTA, citrate)
Assay Type
Sandwich
Detection Range
62.5pg/ml-4000pg/ml
Sensitivity
< 5pg/ml
Preparation and Storage
Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)

Standard Curve (Sample)

(Human sL-Selectin PicoKine ELISA Kit standard curve)

product-image-AAA45277_SC15.jpg Standard Curve (Sample) (Human sL-Selectin PicoKine ELISA Kit standard curve)
Related Product Information for SELL elisa kit
Principle of the assay: human sL-Selectin ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for sL-Selectin has been precoated onto 96-well plates. Standards(NSO,W39 - N332) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for sL-Selectin is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the human sL-Selectin amount of sample captured in plate.
Background: L-selectin, also known as CD62L, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17.SELL (L-selectin) is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins.1 L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point2.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
43,618 Da
NCBI Official Full Name
L-selectin
NCBI Official Synonym Full Names
selectin L
NCBI Official Symbol
SELL
NCBI Official Synonym Symbols
TQ1; LAM1; LEU8; LNHR; LSEL; CD62L; LYAM1; PLNHR; LECAM1
NCBI Protein Information
L-selectin; gp90-MEL; pln homing receptor; lymph node homing receptor; lymphocyte adhesion molecule 1; leukocyte surface antigen Leu-8; CD62 antigen-like family member L; leukocyte-endothelial cell adhesion molecule 1
UniProt Protein Name
L-selectin
UniProt Gene Name
SELL
UniProt Synonym Gene Names
LNHR; LYAM1; LAM-1; LECAM1
UniProt Entry Name
LYAM1_HUMAN

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Product Notes

The Human SELL sell (Catalog #AAA45277) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA45277 ELISA Kit recognizes Human SELL. It is sometimes possible for the material contained within the vial of "sL-Selectin, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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