SDS-PAGE
(>95% as determined by reducing SDS-PAGE)
CD98 recombinant protein
Recombinant Human CD98 Protein
Gene Names
SLC3A2; 4F2; CD98; MDU1; 4F2HC; 4T2HC; NACAE; CD98HC
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
CD98; N/A; Recombinant Human CD98 Protein; 4F2 Cell-Surface Antigen Heavy Chain; 4F2hc; 4F2 Heavy Chain Antigen; Lymphocyte Activation Antigen 4F2 Large Subunit; SLC3A2; MDU1; CD98 recombinant protein
Host
HEK293 Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 mum filtered solution of 20mM PB, 150mM NaCl, 5% Threhalose, pH 7.2.
Sequence
Arg206-Ala630
Sequence Length
631
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
Tag
C-His
Bioactivity
Immobilized Human CD98-His at 2ug/ml (100 ul/well) can bind Anti-Human CD98 mAb. The ED50 of Anti-Human CD98 mAb is 6.50 ng/ml.
Reconstitution
We recommend centrifuging the vial before opening to bring the contents to the bottom. Do not mix by vortex. It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 mg/mL. Concentration is measured by UV-Vis.
Preparation and Storage
Lyophilized proteins are stable for up to 12 months when stored at -20 degree C to -80 degree C.
Reconstituted protein solution can be stored at 4 degree C to 8 degree C for 2 to 7 days.
Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Reconstituted protein solution can be stored at 4 degree C to 8 degree C for 2 to 7 days.
Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
SDS-PAGE
(>95% as determined by reducing SDS-PAGE)
SDS-PAGE
(>95% as determined by reducing SDS-PAGE)
Related Product Information for CD98 recombinant protein
Protein Construction: Recombinant Human CD98 is produced by our Mammalian expression system and the target gene encoding Arg206-Ala630 is expressed with a 6His tag at the C-terminus.
Background: CD98 is a single-pass type I I membrane protein which belongs to the SLC3A transporter family. SLC3A2/MDU1 is expressed ubiquitously in all tissues tested with highest levels detected in kidney, placenta and testis and weakest level in thymus. It consists of an 85 kDa glycosylated type II transmembrane heavy chain and a 40-50 kDa non-glycosylated light chain with 12 transmembrane segments. The heavy chain (SLC3A2) pairs with one of several light chains (SLC7A5, 6, 7, 8, 10, or 11) and is required for the cell surface expression and amino acid transport function of the light chains. It is involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. It also mediates integrin signaling, T cell costimulation, B cell proliferation, and viral fusion with cell membranes.
Background: CD98 is a single-pass type I I membrane protein which belongs to the SLC3A transporter family. SLC3A2/MDU1 is expressed ubiquitously in all tissues tested with highest levels detected in kidney, placenta and testis and weakest level in thymus. It consists of an 85 kDa glycosylated type II transmembrane heavy chain and a 40-50 kDa non-glycosylated light chain with 12 transmembrane segments. The heavy chain (SLC3A2) pairs with one of several light chains (SLC7A5, 6, 7, 8, 10, or 11) and is required for the cell surface expression and amino acid transport function of the light chains. It is involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. It also mediates integrin signaling, T cell costimulation, B cell proliferation, and viral fusion with cell membranes.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated MW: 47.9 kDa
Observed MW: 57-87 kDa
Observed MW: 57-87 kDa
NCBI Official Full Name
4F2 cell-surface antigen heavy chain isoform b
NCBI Official Synonym Full Names
solute carrier family 3 member 2
NCBI Official Symbol
SLC3A2
NCBI Official Synonym Symbols
4F2; CD98; MDU1; 4F2HC; 4T2HC; NACAE; CD98HC
NCBI Protein Information
4F2 cell-surface antigen heavy chain
UniProt Protein Name
4F2 cell-surface antigen heavy chain
UniProt Gene Name
SLC3A2
UniProt Synonym Gene Names
MDU1; 4F2hc
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Product Notes
The CD98 slc3a2 (Catalog #AAA22125) is a Recombinant Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Arg206-Ala 630. It is sometimes possible for the material contained within the vial of "CD98, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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