SDS-PAGE
(Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet.)
STK19 recombinant protein
STK19, Active
Applications
Western Blot
Synonyms
STK19; N/A; STK19, Active; D6S60; D6S60E; G11; HLA-RP1; RP1; STK19 recombinant protein
Host
Sf9 insect cells
Form/Format
Recombinant protein stored in 50mM Tris-HCl, pH7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Applicable Applications for STK19 recombinant protein
WB (Western Blot), Kinase Assay
Tag
GST
Species
Human
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
SDS-PAGE
(Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet.)
SDS-PAGE
(Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet.)
Activity
(Specific Activity: Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.)
Activity
(Specific Activity: Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.)
Related Product Information for STK19 recombinant protein
Recombinant full-length human STK19 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The STK19 gene accession number is NM_004197.
STK19 is a member of the serine/threonine kinase family that shows a manganese-dependent protein kinase activity and phosphorylates alpha-casein at ser/thr residues and histone at ser residues. STK19 contains a positively charged putative nuclear localization signal, multiple potential phosphorylation sites, 2 amidation sites, 9 potential N-myristoylation sites, and no N-glycosylation sites. STK19 has been shown to localize predominantly in the nucleus (1). The phosphorylation of STK19 is thought to be involved in transcriptional regulation. STK19 localizes to the major histocompatibility complex (MHC) class III region on chromosome 6 (2).
STK19 is a member of the serine/threonine kinase family that shows a manganese-dependent protein kinase activity and phosphorylates alpha-casein at ser/thr residues and histone at ser residues. STK19 contains a positively charged putative nuclear localization signal, multiple potential phosphorylation sites, 2 amidation sites, 9 potential N-myristoylation sites, and no N-glycosylation sites. STK19 has been shown to localize predominantly in the nucleus (1). The phosphorylation of STK19 is thought to be involved in transcriptional regulation. STK19 localizes to the major histocompatibility complex (MHC) class III region on chromosome 6 (2).
Product Categories/Family for STK19 recombinant protein
References
1. Gomez-Escobar, N. et.al: The G11 gene located in the major histocompatibility complex encodes a novel nuclear serine/threonine protein kinase. J. Biol. Chem. 273: 30954-30960, 1998.
2. Shen, L. et.al: Structure and genetics of the partially duplicated gene RP located immediately upstream of the complement C4A and the C4B genes in the HLA class III region: molecular cloning, exon-intron structure, composite retroposon, and breakpoint gene duplication. J. Biol. Chem. 269: 8466-8476, 1994.
2. Shen, L. et.al: Structure and genetics of the partially duplicated gene RP located immediately upstream of the complement C4A and the C4B genes in the HLA class III region: molecular cloning, exon-intron structure, composite retroposon, and breakpoint gene duplication. J. Biol. Chem. 269: 8466-8476, 1994.
NCBI and Uniprot Product Information
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Product Notes
The STK19 (Catalog #AAA73965) is a Recombinant Protein produced from Sf9 insect cells and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's STK19 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), Kinase Assay. Researchers should empirically determine the suitability of the STK19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STK19, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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