Application Data
SUV39H2 recombinant protein
SUV39H2 (KMT1B), Active
Gene Names
SUV39H2; KMT1B
Applications
Methyltransferase Assay
Synonyms
SUV39H2; N/A; SUV39H2 (KMT1B), Active; SUV39H2 recombinant protein
Host
Sf9 insect cells using baculovirus
Form/Format
50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Sequence Positions
Full length
Sequence Length
3093
Applicable Applications for SUV39H2 recombinant protein
Methyltransferase Assay
Species
Human
Tag
GST tag
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store product at -70 degree C.
For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature.
For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature.
For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Application Data
Application Data
Application Data
Application Data
Related Product Information for SUV39H2 recombinant protein
Description: Recombinant full-length human SUV39H2 (KMT1B) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Scientific Background: Homo sapiens suppressor of variegation 3-9 homolog 2 (SUV39H2) is encoded by the SUV39H2 gene and belongs to the histone-lysine methyltransferase family and Suvar3-9 subfamily, It contains an N-terminal chromodomain and a C-terminal SET domain. It trimethylates lysine 9 of histone H3, creating a binding site for the chromo domain of HP1 for epigenetic transcriptional repression. Deregulation of SUV39H2 interferes with mammalian higher-order chromatin organization.
Scientific Background: Homo sapiens suppressor of variegation 3-9 homolog 2 (SUV39H2) is encoded by the SUV39H2 gene and belongs to the histone-lysine methyltransferase family and Suvar3-9 subfamily, It contains an N-terminal chromodomain and a C-terminal SET domain. It trimethylates lysine 9 of histone H3, creating a binding site for the chromo domain of HP1 for epigenetic transcriptional repression. Deregulation of SUV39H2 interferes with mammalian higher-order chromatin organization.
Product Categories/Family for SUV39H2 recombinant protein
References
1. Rea S, et al: Regulation of chromatin structure by site-specific histone H3 methyltransferases. Nature.10;406 (6796):593-9, 2000. 2. Aagaard L, et al: Functional mammalian homologues of the Drosophila PEV-modifier Su (var)3-9 encode centromere-associated proteins which complex with the hetero-chromatin component M31. EMBO J. 1;18 (7):1923-38, 1999.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
67 kDa
NCBI Official Full Name
Homo sapiens suppressor of variegation 3-9 homolog 2 (Drosophila), mRNA
NCBI Official Synonym Full Names
suppressor of variegation 3-9 homolog 2
NCBI Official Symbol
SUV39H2
NCBI Official Synonym Symbols
KMT1B
NCBI Protein Information
histone-lysine N-methyltransferase SUV39H2
UniProt Protein Name
Histone-lysine N-methyltransferase SUV39H2
UniProt Gene Name
SUV39H2
UniProt Synonym Gene Names
KMT1B; H3-K9-HMTase 2; Su(var)3-9 homolog 2
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Product Notes
The SUV39H2 suv39h2 (Catalog #AAA73134) is a Recombinant Protein produced from Sf9 insect cells using baculovirus and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Full length. AAA Biotech's SUV39H2 can be used in a range of immunoassay formats including, but not limited to, Methyltransferase Assay. Researchers should empirically determine the suitability of the SUV39H2 suv39h2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SUV39H2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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