SDS-PAGE
TCL1A recombinant protein
TCL1A, 1-114aa, Human, E Coli
Gene Names
TCL1A; TCL1
Applications
SDS-Page
Purity
> 90% by SDS-PAGE
Synonyms
TCL1A; N/A; TCL1A, 1-114aa, Human, E Coli; T-cell leukemia/lymphoma 1A; TCL1; TCL-1; protein p14TCL1; Oncogene TCL1; T-cell leukemia/lymphoma 1A anti TCL1A; P14 TCL1; P14 TCL1 protein; T cell leukemia 1; T cell lymphoma 1; T cell lymphoma 1A; TCL 1 protein; TCL1 oncogene; TCL1 PEN; TCL1A.; TCL1A recombinant protein
Host
E Coli
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. In 50mM Tris-HCl Buffer (pH 7.5) containing 10% glycerol
Concentration
1 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MAECPTLGEA VTDHPDRLWA WEKFVYLDEK QHAWLPLTIE IKDRLQLRVL LRREDVVLGR PMTPTQIGPS LLPIMWQLYP DGRYRSSDSS FWRLVYHIKI DGVEDMLLEL LPDD
Sequence Length
114
Applicable Applications for TCL1A recombinant protein
SDS-PAGE
Antigen Species
Human
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
SDS-PAGE
SDS-PAGE
Related Product Information for TCL1A recombinant protein
TCL1A, also known as T-cell leukemia/lymphoma 1A, is a protein with a suggested role in intracellular regulation of T cell signaling. TCL1A binds to the pleckstrin homology domain of Akt (protein kinase B) family proteins, which facilitates Akt dimerization and activity. By increasing Akt activity TCL1A may enhance the serine/threonine phosphorylation of major Akt signaling substrates, such as Ikk complex, mTOR, BAD, p70S6 kinase, FOXO transcription factors, and GSK3b. These substrates regulate cellular differentiation, growth, survival, and metabolism. Recombinant TCL1A protein was expressed in E Coli and purified by using conventional chromatography techniques
Product Categories/Family for TCL1A recombinant protein
References
Herling M., et al. (2006) Leukemia. 20 (2):280-5.; Hoyer KK., et al. (2005) J Immunol. 175 (2):864-73.;
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
13.4 kDa (114aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)
NCBI Official Full Name
T-cell leukemia/lymphoma protein 1A
NCBI Official Synonym Full Names
T cell leukemia/lymphoma 1A
NCBI Official Symbol
TCL1A
NCBI Official Synonym Symbols
TCL1
NCBI Protein Information
T-cell leukemia/lymphoma protein 1A
UniProt Protein Name
T-cell leukemia/lymphoma protein 1A
UniProt Gene Name
TCL1A
UniProt Synonym Gene Names
TCL1; Oncogene TCL1
Similar Products
Product Notes
The TCL1A tcl1a (Catalog #AAA48561) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TCL1A can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the TCL1A tcl1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MAECPTLGEA VTDHPDRLWA WEKFVYLDEK QHAWLPLTIE IKDRLQLRVL LRREDVVLGR PMTPTQIGPS LLPIMWQLYP DGRYRSSDSS FWRLVYHIKI DGVEDMLLEL LPDD. It is sometimes possible for the material contained within the vial of "TCL1A, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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