Troponin I Type 2 Recombinant Protein | TNNI2 recombinant protein
Recombinant Human Troponin I Type 2
Gene Names
TNNI2; DA2B; FSSV; fsTnI; AMCD2B
Purity
Greater than 85.0% as determined by SDS-PAGE.
Synonyms
Troponin I Type 2; N/A; Recombinant Human Troponin I Type 2; TNNI2 Human; Troponin I Type 2 Human Recombinant; Troponin I fast skeletal muscle; Troponin I fast-twitch isoform; TNNI2; DA2B; FSSV; fsTnI; AMCD2B; TNNI2 recombinant protein
Host
E Coli
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Form/Format
The protein solution contains 20mM Tris-HCl, 500mM NaCl and 10mM b-ME, pH 7.5.
Sterile Filtered colourless liquid formualtion.
Sterile Filtered colourless liquid formualtion.
Sequence Length
182
Preparation and Storage
TNNI2 Human although stable at 10 degree C for 7 days, should be stored below -18 degree C.Please prevent freeze-thaw cycles.
Related Product Information for TNNI2 recombinant protein
Description: Skeletal isoforms of Troponin I were suggested to be used as markers of acute and chronic skeletal muscle injuries. In skeletal muscles Troponin I is presented by two forms, slow (21.6 kDa) and fast (21.2 kDa) skeletal. The protein (Fast Skeletal Troponin I) migrates on SDS-PAGE to approximately 26.5kDa.
Introduction: TNNI2 is a fast-twitch skeletal muscle protein, belongs to the troponin I gene family, and is part of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, together with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. TNNI2 is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. Other than muscle tissues, TNNI2 is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a coactivator of estrogen receptor-related receptor alpha. Furthermore, TNNI2 suppresses tumor growth in human ovarian carcinoma. Mutations in the TNNI2 gene cause myopathy and distal arthrogryposis type 2B.
Introduction: TNNI2 is a fast-twitch skeletal muscle protein, belongs to the troponin I gene family, and is part of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, together with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. TNNI2 is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. Other than muscle tissues, TNNI2 is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a coactivator of estrogen receptor-related receptor alpha. Furthermore, TNNI2 suppresses tumor growth in human ovarian carcinoma. Mutations in the TNNI2 gene cause myopathy and distal arthrogryposis type 2B.
Product Categories/Family for TNNI2 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21,355 Da
NCBI Official Full Name
troponin I, fast skeletal muscle isoform 1
NCBI Official Synonym Full Names
troponin I type 2 (skeletal, fast)
NCBI Official Symbol
TNNI2
NCBI Official Synonym Symbols
DA2B; FSSV; fsTnI; AMCD2B
NCBI Protein Information
troponin I, fast skeletal muscle; troponin I fast twitch 2; troponin I, fast-twitch isoform; troponin I, fast-twitch skeletal muscle isoform; troponin I, skeletal, fast
UniProt Protein Name
Troponin I, fast skeletal muscle
UniProt Gene Name
TNNI2
UniProt Entry Name
TNNI2_HUMAN
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Product Notes
The TNNI2 tnni2 (Catalog #AAA38441) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Troponin I Type 2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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