Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
32-834. Partial, provide the complete extracellular domain.
Sequence
GKTMTSHVISVVETSQLLVDNAVYNTMKRNLKKRGVLSPAQLLSFSKLPESTSGAISRAAEIMETSIQVMKREQSQFSTDALSADILATIANLSGCLPFMLPPRCPDTCLANKYRPITGVCNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPNFLYHGFPLPPVREVTRHLIQVSNEAVTEDDQYSDFLPVWGQYIDHDIALTPQSTSTAAFWGGVDCQLTCENQNPCFPIQLPSNSSRTTACLPFYRSSAACGTGDQGALFGNLSAANPRQQMNGLTSFLDASTVYGSSPGVEKQLRNWSSSAGLLRVNTLHLDSGRAYLPFASAACAPEPGAPHANRTPCFLAGDGRASEVPALAAVHTLWLREHNRLATAFKAINTHWSANTAYQEARKVVGALHQIITMRDYIPKILGPDAFRQYVGPYEGYNPTVNPTVSNVFSTAAFRFGHATVHPLVRRLNTDFQDHTELPRLQLHDVFFRPWRLIQEGGLDPIVRGLLARPAKLQVQEQLMNEELTERLFVLSNVGTLDLASLNLQRGRDHGLPGYNEWREFCGLSRLDTGAELNKAIANRSMVNKIMELYKHADNIDVWLGGLAEKFLPGARTGPLFACIIGKQMKALRDGDRFWWENSHVFTDAQRQELEKHSLPRVICDNTGLTRVPVDAFRIGKFPQDFESCEEIPSMDLRLWRETFPQDDKCVFPEKVDNGNFVHCEESGKLVLVYSCFHGYKLQGQEQVTCTQNGWDSEPPVCKDVNECADLTHPPCHSSAKCKNTKGSFQCVCTDPYMLGEDEKTCIDSGRLPR
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Related Product Information for TPO recombinant protein
Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T3 and T4.
References
Complete nucleotide sequence of the cDNA for thyroid peroxidase in FRTL5 rat thyroid cells.Derwahl M., Seto P., Rapoport B.Nucleic Acids Res. 17:8380-8380(1989) Thyroid peroxidase rat cDNA sequence, chromosomal localization in mouse, and regulation of gene expression by comparison to thyroglobulin in rat FRTL-5 cells.Isozaki O., Kohn L.D., Kozak C.A., Kimura S.Mol. Endocrinol. 3:1681-1692(1989)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
116.4KD
NCBI Official Full Name
Thyroid peroxidase
NCBI Official Synonym Full Names
thyroid peroxidase
NCBI Official Symbol
Tpo
NCBI Protein Information
thyroid peroxidase
UniProt Protein Name
Thyroid peroxidase
UniProt Gene Name
Tpo
UniProt Synonym Gene Names
TPO
UniProt Entry Name
PERT_RAT
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Product Notes
The TPO tpo (Catalog #AAA113659) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 32-834. Partial, provide the complete extracellular domain. The amino acid sequence is listed below: GKTMTSHVIS VVETSQLLVD NAVYNTMKRN LKKRGVLSPA QLLSFSKLPE STSGAISRAA EIMETSIQVM KREQSQFSTD ALSADILATI ANLSGCLPFM LPPRCPDTCL ANKYRPITGV CNNRDHPRWG ASNTALARWL PPVYEDGFSQ PRGWNPNFLY HGFPLPPVRE VTRHLIQVSN EAVTEDDQYS DFLPVWGQYI DHDIALTPQS TSTAAFWGGV DCQLTCENQN PCFPIQLPSN SSRTTACLPF YRSSAACGTG DQGALFGNLS AANPRQQMNG LTSFLDASTV YGSSPGVEKQ LRNWSSSAGL LRVNTLHLDS GRAYLPFASA ACAPEPGAPH ANRTPCFLAG DGRASEVPAL AAVHTLWLRE HNRLATAFKA INTHWSANTA YQEARKVVGA LHQIITMRDY IPKILGPDAF RQYVGPYEGY NPTVNPTVSN VFSTAAFRFG HATVHPLVRR LNTDFQDHTE LPRLQLHDVF FRPWRLIQEG GLDPIVRGLL ARPAKLQVQE QLMNEELTER LFVLSNVGTL DLASLNLQRG RDHGLPGYNE WREFCGLSRL DTGAELNKAI ANRSMVNKIM ELYKHADNID VWLGGLAEKF LPGARTGPLF ACIIGKQMKA LRDGDRFWWE NSHVFTDAQR QELEKHSLPR VICDNTGLTR VPVDAFRIGK FPQDFESCEE IPSMDLRLWR ETFPQDDKCV FPEKVDNGNF VHCEESGKLV LVYSCFHGYK LQGQEQVTCT QNGWDSEPPV CKDVNECADL THPPCHSSAK CKNTKGSFQC VCTDPYMLGE DEKTCIDSGR LPR. It is sometimes possible for the material contained within the vial of "Thyroid peroxidase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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