SDS-PAGE
T cell receptor alpha constant (TRAC) Recombinant Protein | TRAC recombinant protein
Recombinant Human T cell receptor alpha constant (TRAC)
Gene Names
TRAC; TRA; IMD7; TCRA; TRCA
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
T cell receptor alpha constant (TRAC); N/A; Recombinant Human T cell receptor alpha constant (TRAC); TRAC recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-142aa; Full Length Protein;
Sequence
PNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKTVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPSPESSCDVKLVEKSFETDTNLNFQNLSVIGFRILLLKVAGFNLLMTLRLWSS
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
SDS-PAGE
SDS-PAGE
Product Categories/Family for TRAC recombinant protein
References
The chromosomal location of T-cell receptor genes and a T cell rearranging gene possible correlation with specific translocations in human T cell leukaemia.Rabbitts T.H., Lefranc M.P., Stinson M.A., Sims J.E., Schroder J., Steinmetz M., Spurr N.L., Solomon E., Goodfellow P.N.EMBO J. 4:1461-1465(1985) Analysis of cDNA clones specific for human T cells and the alpha and beta chains of the T-cell receptor heterodimer from a human T-cell line.Yanagi Y., Chan A., Chin B., Minden M., Mak T.W.Proc. Natl. Acad. Sci. U.S.A. 82:3430-3434(1985) Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M., Schiess R., Aebersold R., Watts J.D.Nat. Biotechnol. 27:378-386(2009) Mutation in the TCRalpha subunit constant gene (TRAC) leads to a human immunodeficiency disorder characterized by a lack of TCRalphabeta+ T cells.Morgan N.V., Goddard S., Cardno T.S., McDonald D., Rahman F., Barge D., Ciupek A., Straatman-Iwanowska A., Pasha S., Guckian M., Anderson G., Huissoon A., Cant A., Tate W.P., Hambleton S., Maher E.R.J. Clin. Invest. 121:695-702(2011) The 1.5 A crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance.Kjer-Nielsen L., Clements C.S., Brooks A.G., Purcell A.W., McCluskey J., Rossjohn J.Structure 10:1521-1532(2002) A structural basis for immunodominant human T cell receptor recognition.Stewart-Jones G.B.E., McMichael A.J., Bell J.I., Stuart D.I., Jones E.Y.Nat. Immunol. 4:657-663(2003) Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule.Li Y., Huang Y., Lue J., Quandt J.A., Martin R., Mariuzza R.A.EMBO J. 24:2968-2979(2005)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
17.9 kDa
NCBI Official Full Name
T-cell receptor alpha chain C region
NCBI Official Synonym Full Names
T-cell receptor alpha constant
NCBI Official Symbol
TRAC
NCBI Official Synonym Symbols
TRA; IMD7; TCRA; TRCA
UniProt Protein Name
T-cell receptor alpha chain C region
UniProt Gene Name
TRAC
UniProt Synonym Gene Names
TCRA
UniProt Entry Name
TCA_HUMAN
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Product Notes
The TRAC trac (Catalog #AAA113614) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-142aa; Full Length Protein;. The amino acid sequence is listed below: PNIQNPDPAV YQLRDSKSSD KSVCLFTDFD SQTNVSQSKD SDVYITDKTV LDMRSMDFKS NSAVAWSNKS DFACANAFNN SIIPEDTFFP SPESSCDVKL VEKSFETDTN LNFQNLSVIG FRILLLKVAG FNLLMTLRLW SS. It is sometimes possible for the material contained within the vial of "T cell receptor alpha constant (TRAC), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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