Application Data
ViraDuctin AAV Transduction Kit
ViraDuctin AAV Transduction Kit (50 Transductions)
Synonyms
ViraDuctin AAV; N/A; ViraDuctin AAV Transduction Kit (50 Transductions); ViraDuctin AAV transduction kit
Preparation and Storage
Store kit components at -20 degree C until their expiration dates. Avoid multiple freeze/thaws by aliquoting.
Application Data
Application Data
Application Data
Application Data
Related Product Information for ViraDuctin AAV transduction kit
Background: The viral system includes vectors developed from retrovirus (RV), adenovirus (AdV), adeno-associated virus (AAV), lentivirus (LV), and herpes simplex virus (HSV). AAV belongs to the family of Parvoviridae, a group of viruses among the smallest of single-stranded and non-enveloped DNA viruses. There are eight different AAV serotypes reported to date. Recombinant AAV-2 is the most common serotype used in gene delivery, and can be produced at high titers with a helper virus or AAV Helper-Free System. AAV can infect both dividing and non-dividing cells and can be maintained in the human host cell, creating the potential for genome integration. Because AAV is a naturally defective virus, requiring provision of several factors in trans for productive infection, it is considered the safest viral vector to use. These factors make AAV an attractive vector for gene therapy. The AAV transduction process includes viral binding and entry, intracellular trafficking, nuclear transport, and viral second strand DNA synthesis. The viral second strand DNA synthesis has been shown to be the rate limiting step, which leads to inefficient transduction by AAV vectors.
Product Categories/Family for ViraDuctin AAV transduction kit
References
1. Rabinowitz, J, and Samulski, R. J. (1998). Curr. Opin. Biotechnol., 9, 470-475.2. Summer ford, C., and Samulski, R. J. (1999). Nat. Med., 5, 587-588.3. Clark, K., Liu, X., McGrath, J., and Johnson, P. (1999). Hum. Gene Ther., 10, 1031-1039.
Nazari, M. et al. (2014). AAV2-mediated follistatin overexpression induces ovine primary myoblasts proliferation. BMC Biotechnol. 14:87.
Nazari, M. et al. (2014). AAV2-mediated follistatin overexpression induces ovine primary myoblasts proliferation. BMC Biotechnol. 14:87.
Similar Products
Product Notes
The ViraDuctin AAV (Catalog #AAA44622) is a Transduction Kit and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ViraDuctin AAV, Transduction Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.