Tripartite Motif Containing 21 Recombinant Protein | TRIM21 recombinant protein
Recombinant Human Tripartite Motif Containing 21 (RO52)
Gene Names
TRIM21; SSA; RO52; SSA1; RNF81; Ro/SSA
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
Tripartite Motif Containing 21; N/A; Recombinant Human Tripartite Motif Containing 21 (RO52); 52 kDa Ro protein, Sjoegren syndrome type A antigen, SS-A, Ro(SS-A), 52 kDa ribonucleoprotein autoantigen Ro/SS-A, Tripartite motif-containing protein 21, RING finger protein 81, TRIM21, RNF81, RO52, SSA1, SSA, RO-52.; TRIM21 recombinant protein
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
TRIM21 solution (1.01 mg/ml) supplied in 20mM HEPES pH-7.5, 0.01mM EDTA and 0.02% SDS.
Sequence Length
475
Source
Sf9 Insect Cells
Physical Appearance
Sterile Filtered clear solution.
Preparation and Storage
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
Related Product Information for TRIM21 recombinant protein
Description: TRIM21 Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 54,922 Dalton. TRIM21 is expressed with a -6x His tag at N-terminus and purified by proprietary chromatographic techniques.
Introduction: TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The 52 kDa Ro protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. Ro/SSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Ribonucleoprotein particle is composed of a single polypeptide and one of four small RNA molecules. The RoSSA is present in all mammalian cells studied but has no known function. At least 2 isoforms are present in nucleated and red blood cells, and tissue specific differences in Ro/SSA proteins were identified.
Introduction: TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The 52 kDa Ro protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. Ro/SSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Ribonucleoprotein particle is composed of a single polypeptide and one of four small RNA molecules. The RoSSA is present in all mammalian cells studied but has no known function. At least 2 isoforms are present in nucleated and red blood cells, and tissue specific differences in Ro/SSA proteins were identified.
Product Categories/Family for TRIM21 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
E3 ubiquitin-protein ligase TRIM21
NCBI Official Synonym Full Names
tripartite motif containing 21
NCBI Official Symbol
TRIM21
NCBI Official Synonym Symbols
SSA; RO52; SSA1; RNF81; Ro/SSA
NCBI Protein Information
E3 ubiquitin-protein ligase TRIM21; 52 kDa Ro protein; 52 kDa ribonucleoprotein autoantigen Ro/SS-A; RING finger protein 81; Sicca syndrome antigen A; Sjogren syndrome antigen A1 (52kDa, ribonucleoprotein autoantigen SS-A/Ro); ro(SS-A); sjoegren syndrome type A antigen; tripartite motif-containing 21; tripartite motif-containing protein 21
UniProt Protein Name
E3 ubiquitin-protein ligase TRIM21
UniProt Gene Name
TRIM21
UniProt Synonym Gene Names
RNF81; RO52; SSA1; SS-A
UniProt Entry Name
RO52_HUMAN
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Product Notes
The TRIM21 trim21 (Catalog #AAA38432) is a Recombinant Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Tripartite Motif Containing 21, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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