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product-image-AAA47603_SDS_PAGE13.jpg SDS-PAGE (Figure 1. Human ALPP Protein, His Tag on SDS-PAGE under reducing condition.)

ALPP recombinant protein

Human ALPP Protein, His Tag

Gene Names
ALPP; ALP; PALP; PLAP; PLAP-1
Purity
Purified from cell culture supernatant by affinity chromatography
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Synonyms
ALPP; N/A; Human ALPP Protein, His Tag; ALP; ALPI; IAP; PALP; PLAP; PLAP-1; ALPP recombinant protein
Ordering
Host
HEK293
Purity/Purification
Purified from cell culture supernatant by affinity chromatography
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Form/Format
Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose is added as protectants before lyophilization.
Sequence
ALPP(Ile23-Thr505) 6×His tag
Tag
C-6×His Tag
Preparation and Storage
Store at -20 degree C to -80 degree C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80 degree C (Avoid repeated freezing and thawing).

SDS-PAGE

(Figure 1. Human ALPP Protein, His Tag on SDS-PAGE under reducing condition.)

product-image-AAA47603_SDS_PAGE13.jpg SDS-PAGE (Figure 1. Human ALPP Protein, His Tag on SDS-PAGE under reducing condition.)

ELISA

(Figure 1. Human ALPP Protein, His Tag on SDS-PAGE under reducing condition.)

product-image-AAA47603_ELISA15.jpg ELISA (Figure 1. Human ALPP Protein, His Tag on SDS-PAGE under reducing condition.)
Related Product Information for ALPP recombinant protein
Recombinant Human ALPP Protein with C-terminal 6×His tag
The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. One of the main sources of this enzyme is the liver, and thus, it's one of several indicators of liver injury in different clinical conditions. In pregnant women, this protein is primarily expressed in placental and endometrial tissue, however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Aug 2020]
Product Categories/Family for ALPP recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
250
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
57,954 Da
NCBI Official Full Name
alkaline phosphatase, placental type preproprotein
NCBI Official Synonym Full Names
alkaline phosphatase, placental
NCBI Official Symbol
ALPP
NCBI Official Synonym Symbols
ALP; PALP; PLAP; PLAP-1
NCBI Protein Information
alkaline phosphatase, placental type; Regan isozyme; glycerophosphatase; alkaline phosphomonoesterase; placental alkaline phosphatase 1; alkaline phosphatase Regan isozyme
UniProt Protein Name
Alkaline phosphatase, placental type
UniProt Gene Name
ALPP
UniProt Synonym Gene Names
PLAP; PLAP-1
UniProt Entry Name
PPB1_HUMAN

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Product Notes

The ALPP alpp (Catalog #AAA47603) is a Recombinant Protein produced from HEK293 and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ALPP(Ile23 -Thr505) 6×His tag. It is sometimes possible for the material contained within the vial of "ALPP, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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