DNA dC->dU-editing enzyme APOBEC-3A (APOBEC3A) Recombinant Protein | APOBEC3A recombinant protein

Recombinant Human DNA dC->dU-editing enzyme APOBEC-3A (APOBEC3A)

Cat. Num. AAA18473

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: DNA dC->dU-editing enzyme APOBEC-3A (APOBEC3A); N/A; Recombinant Human DNA dC->dU-editing enzyme APOBEC-3A (APOBEC3A); Phorbolin-1; APOBEC3A recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-199aa; Full Length
• Sequence: MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN

• Species: Homo sapiens (Human)
• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

Related Product Information for APOBEC3A recombinant protein

DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.

Product Categories/Family for APOBEC3A recombinant protein

Signal Transduction

References

"Psoriasis upregulated phorbolin-1 shares structural but not functional similarity to the mRNA-editing protein apobec-1." Madsen P.P., Anant S., Rasmussen H.H., Gromov P., Vorum H., Dumanski J.P., Tommerup N., Collins J.E., Wright C.L., Dunham I., Macginnitie A.J., Davidson N.O., Celis J.E. J. Invest. Dermatol. 113:162-169(1999)

NCBI and Uniprot Product Information

• NCBI GI #: 300869638
• NCBI GeneID: 100913187
• NCBI Accession #: NP_001180218.1
• NCBI GenBank Nucleotide #: NM_001193289.1
• UniProt Accession #: P31941; Q12807; Q5JZ93; Q9UH18; A0AVM1
• Molecular Weight: 39 kDa
• NCBI Official Full Name: probable DNA dC->dU-editing enzyme APOBEC-3A
• NCBI Official Synonym Full Names: APOBEC3A and APOBEC3B deletion hybrid
• NCBI Official Symbol: APOBEC3A_B
• NCBI Protein Information: probable DNA dC->dU-editing enzyme APOBEC-3A
• UniProt Protein Name: DNA dC->dU-editing enzyme APOBEC-3A
• UniProt Gene Name: APOBEC3A
• UniProt Synonym Gene Names: A3A
• UniProt Entry Name: ABC3A_HUMAN