Beta-2-microglobulin (B2M) Recombinant Protein | B2M recombinant protein
Recombinant Human Beta-2-microglobulin (B2M), partial
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Beta-2-microglobulin (B2M); N/A; Recombinant Human Beta-2-microglobulin (B2M), partial; B2M recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
22-119aa; Partial(Beta-2-microglobulin form pI 5.3 Chain)
Sequence
QRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDR DM
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Related Product Information for B2M recombinant protein
Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP) [MIM:241600]. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation.
References
[1] "The beta-2-microglobulin mRNA in human Daudi cells has a mutated initiation codon but is still inducible by interferon." Rosa F., Berissi H., Weissenbach J., Maroteaux L., Fellous M., Revel M. EMBO J. 2:239-243(1983)
[2] "Isolation of a granulocyte inhibitory protein from uraemic patients with homology of beta 2-microglobulin." Haag-Weber M., Mai B., Hoerl W.H. Nephrol. Dial. Transplant. 9:382-388(1994)
[2] "Isolation of a granulocyte inhibitory protein from uraemic patients with homology of beta 2-microglobulin." Haag-Weber M., Mai B., Hoerl W.H. Nephrol. Dial. Transplant. 9:382-388(1994)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
15 KD
NCBI Official Full Name
beta-2-microglobulin
NCBI Official Synonym Full Names
beta-2-microglobulin
NCBI Official Symbol
B2M
NCBI Protein Information
beta-2-microglobulin; OTTHUMP00000161912; beta-2-microglobin; beta chain of MHC class I molecules
UniProt Protein Name
Beta-2-microglobulin
UniProt Gene Name
B2M
UniProt Entry Name
B2MG_HUMAN
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Product Notes
The B2M b2m (Catalog #AAA81596) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 22-119aa; Partial(Beta-2-microglobulin form pI 5.3 Chain). The amino acid sequence is listed below: QRTPKIQVYS RHPAENGKSN FLNCYVSGFH PSDIEVDLLK NGERIEKVEH SDLSFSKDWS FYLLYYTEFT PTEKDEYACR VNHVTLSQPK IVKWDR DM. It is sometimes possible for the material contained within the vial of "Beta-2-microglobulin (B2M), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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