Bioactivity
(Human CSH1 stimulates cell proliferation of the Nb2-11 Rat lymphoma cells. The ED50 range )
Placental Lactogen/CSH1 Active Protein | CSH1 active protein
Recombinant Human Placental Lactogen/CSH1 Protein
Gene Names
CSH1; PL; CSA; CS-1; CSMT; hCS-1; hCS-A
Applications
SDS-Page
Purity
>90% by SDS-PAGE
Synonyms
Placental Lactogen/CSH1; N/A; Recombinant Human Placental Lactogen/CSH1 Protein; chorionic somatomammotropin hormone 1 precursor; chorionic somatomammotropin A; choriomammotropin; placental lactogen; PL; chorionic somatomammotropin-1; Lactogen; CS-1; CSA; CSMT; CHB3; hcs-1; hcs-A; CSH1; CSH1 active protein
Host
Baculovirus
Purity/Purification
>90% by SDS-PAGE
Form/Format
Liquid. In Phosphate-Buffered Saline (pH7.4) containing 30% glycerol
Concentration
0.25mg/ml (determined by Absorbance at 280nm) (varies by lot)
Sequence Positions
27-217aa
Sequence
VQTVPLSRLF DHAMLQAHRA HQLAIDTYQE FEETYIPKDQ KYSFLHDSQT SFCFSDSIPT PSNMEETQQK SNLELLRISL LLIESWLEPV RFLRSMFANN LVYDTSDSDD YHLLKDLEEG IQTLMGRLED GSRRTGQILK QTYSKFDTNS HNHDALLKNY GLLYCFRKDM DKVETFLRMV QCRSVEGSCG F
Applicable Applications for CSH1 active protein
Bioactivity, SDS-PAGE
Endotoxin
<1 EU per 1ug of protein (determined by LAL method)
Species
Human
Tag
His-Tag
Predicted N-term
Val
Bioactivity
Measured in a cell proliferation assay using Nb2-11 Rat lymphoma cells. The ED50 range <= 0.8ng/ml.
Preparation and Storage
Can be stored at +2C to +8 degree C for 1 week. For long term storage, aliquot and store at -20C to -80 degree C. Avoid repeated freezing and thawing cycles.
Bioactivity
(Human CSH1 stimulates cell proliferation of the Nb2-11 Rat lymphoma cells. The ED50 range )
Bioactivity
(Human CSH1 stimulates cell proliferation of the Nb2-11 Rat lymphoma cells. The ED50 range )
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
SDS-PAGE
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
Related Product Information for CSH1 active protein
CSH1, also known as placental lactogen, is a member of the PRL/GH family. CSH1 gene is located on chromosome 17q which participates in the regulation of postnatal and intrauterine growth. This protein is produced only during preganancy and plays important role in increase of pancreatic islets. It also inhibits apoptosis of insulinoma cell lines by activating the phosphorylation of AKT protein. CSH1 activates PRLR through zinc-induced dimerization but does not interact with GHR. Recombinant human CSH1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Categories/Family for CSH1 active protein
References
Prager S., et al, (2003) Genet Test. 7:259-263. Uemura S, et al, (2007) J Biol Chem. 282:8613-8621. Awonuga AO, et al, (2011) Mol Reprod Dev. 78:519-528.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
25,020 Da
NCBI Official Full Name
chorionic somatomammotropin hormone 1
NCBI Official Synonym Full Names
chorionic somatomammotropin hormone 1 (placental lactogen)
NCBI Official Symbol
CSH1
NCBI Official Synonym Symbols
PL; CSA; CS-1; CSMT; hCS-1; hCS-A
NCBI Protein Information
chorionic somatomammotropin hormone 1; choriomammotropin; chorionic somatomammotropin A; chorionic somatomammotropin-1; placental lactogen
UniProt Protein Name
Chorionic somatomammotropin hormone 1
UniProt Gene Name
CSH1
UniProt Synonym Gene Names
Choriomammotropin; PL
UniProt Entry Name
CSH1_HUMAN
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Product Notes
The CSH1 csh1 (Catalog #AAA48364) is an Active Protein produced from Baculovirus and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 27-217aa. AAA Biotech's Placental Lactogen/CSH1 can be used in a range of immunoassay formats including, but not limited to, Bioactivity, SDS-PAGE. Researchers should empirically determine the suitability of the CSH1 csh1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: VQTVPLSRLF DHAMLQAHRA HQLAIDTYQE FEETYIPKDQ KYSFLHDSQT SFCFSDSIPT PSNMEETQQK SNLELLRISL LLIESWLEPV RFLRSMFANN LVYDTSDSDD YHLLKDLEEG IQTLMGRLED GSRRTGQILK QTYSKFDTNS HNHDALLKNY GLLYCFRKDM DKVETFLRMV QCRSVEGSCG FPrecautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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