Structure
(Vevorisertib trihydrochloride, CAS 1416775-08-0)
Arachidonoyl-L-carnitine (chloride) Biochemical
Arachidonoyl-L-carnitine (chloride)
Purity
98%
Synonyms
Arachidonoyl-L-carnitine (chloride); N/A; ARQ 751 trihydrochloride; Arachidonoyl-L-carnitine (chloride) biochemical
Purity/Purification
98%
Solubility
PBS (pH 7.2): 10 mg/mL
Ethanol: 30 mg/mL
DMSO: 10 mg/mL
DMF: 20 mg/mL
<1mg/ml refers to the product slightly soluble or insoluble
Ethanol: 30 mg/mL
DMSO: 10 mg/mL
DMF: 20 mg/mL
<1mg/ml refers to the product slightly soluble or insoluble
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(Vevorisertib trihydrochloride, CAS 1416775-08-0)
Structure
(Vevorisertib trihydrochloride, CAS 1416775-08-0)
Structure
(Vevorisertib trihydrochloride, CAS 1416775-08-0)
Structure
(Vevorisertib trihydrochloride, CAS 1416775-08-0)
Related Product Information for Arachidonoyl-L-carnitine (chloride) biochemical
Carnitine facilitates the transport of fatty acids into the mitochondria to be used in fatty acid metabolism. It does so by accepting acyl groups from fatty acids complexed with coenzyme A, which yields esterified carnitine or acylcarnitines that enable the transport of fatty acyl groups into the inner mitochondrial matrix. beta-Oxidation of fatty acids in mitochondria is inhibited by uncoupling conditions, thus changes in circulating levels of various acylcarnitines have been used to identify alterations in metabolic state.[1] [2] Arachidonoyl-L-carnitine formed from carnitine conjugated to arachidonic acid.
References
1. Yu Y, et al. Targeting AKT1-E17K and the PI3K/AKT Pathway with an Allosteric AKT Inhibitor, ARQ 092. PLoS One. 2015 Oct 15;10(10):e0140479.
2. Kozinova M, et al. Combined Inhibition of AKT and KIT Restores Expression of Programmed Cell Death 4 (PDCD4) in Gastrointestinal Stromal Tumor. Cancers (Basel). 2021 Jul 23;13(15):3699.
2. Kozinova M, et al. Combined Inhibition of AKT and KIT Restores Expression of Programmed Cell Death 4 (PDCD4) in Gastrointestinal Stromal Tumor. Cancers (Basel). 2021 Jul 23;13(15):3699.
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Product Notes
The Arachidonoyl-L-carnitine (chloride) (Catalog #AAA227295) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Arachidonoyl-L-carnitine (chloride), Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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