Structure
(7-TFA-ap-7-Deaza-ddA, CAS 114748-71-9)
beta-Amyloid Biochemical
beta-Amyloid (1-42), (rat/mouse)(TFA)
Purity
98%
Synonyms
beta-Amyloid; N/A; beta-Amyloid (1-42), (rat/mouse)(TFA); beta-Amyloid biochemical
Purity/Purification
98%
Solubility
DMSO: 55 mg/mL (12.14 mM),
Need ultrasonic
<1mg/ml refers to the product slightly soluble or insoluble
Need ultrasonic
<1mg/ml refers to the product slightly soluble or insoluble
In vitro
beta-Amyloid Aggregation Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs). 1. Solid Abeta peptide was dissolved in cold hexafluoro-2-propanol (HFIP). The peptide was incubated at room temperature for at least 1h to establish monomerization and randomization of structure. 2. The HFIP was removed by evaporation, and the resulting peptide was stored as a film at -20 or -80 degree C. 3. The resulting film was dissolved in anhydrous DMSO at 5 mM and then diluted into the appropriate concentration and buffer (serum- and phenol red-free culture medium) with vortexing. 4. Next, the solution was aged 48h at 4-8 degree C. The sample was then centrifuged at 14000g for 10 min at 4-8 degree C; the soluble oligomers were in the supernatant. The supernatant was diluted 10-200-fold for experiments. Methods vary depends on the downstream applications.
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(7-TFA-ap-7-Deaza-ddA, CAS 114748-71-9)
Structure
(7-TFA-ap-7-Deaza-ddA, CAS 114748-71-9)
Structure
(7-TFA-ap-7-Deaza-ddA, CAS 114748-71-9)
Structure
(7-TFA-ap-7-Deaza-ddA, CAS 114748-71-9)
Related Product Information for beta-Amyloid biochemical
beta-Amyloid (1-42), (rat/mouse) TFA is a 42-aa peptide, shows cytotoxic effect on acute hippocampal slices, and used in the research of Alzheimer's disease.
References
1. Shen G, et, al. Thiotriphosphate nucleotide dye terminators. US20060281100A1.
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Product Notes
The beta-Amyloid (Catalog #AAA227035) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "beta-Amyloid, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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